APLP2

amyloid beta (A4) precursor-like protein 2

APLP2 is amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

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Products

Antibodies (45)

Proteins (8)

ELISA Kits (3)

Type

Cell-Based (1)

Over-Expression Lysate (4)

Primary (45)

Recombinant (4)

Sandwich (2)

Target

APLP2 (56)

Reactivity

Human (48)

Mouse (21)

Rat (14)

Bat (1)

Dog (1)

Monkey (1)

Application

IHC (17)

IHC-P (5)

WB (39)

ELISA (15)

IF (1)

Peptide-ELISA (4)

Host

rabbit (43)

mouse (2)

Product Group

IHCPlus (1)

Isotype

IgG (27)

IgG2b (1)

IgG2b,k (1)

Clonality

monoclonal mc (2)

polyclonal pc (43)

Clone

11n11 (1)

4B5 (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (2)

APC (1)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (3)

Unconjugated (25)

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Epitope

aa1-210 (8)

aa593-621 (6)

Internal (4)

pTyr755 (2)

210-290 aa, Internal (1)

690-770 aa (1)

C-Terminus (1)

Tyr274 (1)

aa241-290 (1)

aa256-295 (1)

aa262-491 (1)

aa30-680 (1)

aa340-450 (1)

aa639-656 (1)

aa714-763 (1)

p755 (1)

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Publications

No (56)

Sample Type

Adherent Cell Cultures (1)

Plasma (1)

Serum (1)

Tissue Homogenates (2)

Tag

GST (1)

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (5)

Species

Human (6)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

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APLP2 Antibody LS-C334068

Antibody:

APLP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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APLP2 Antibody (aa262-491) LS-C179025

Antibody:

APLP2 Rabbit anti-Human Polyclonal (aa262-491) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$332

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IHC-plus™ APLP2 Antibody (aa256-295) LS-B13316

(4.0) Rating

Antibody:

APLP2 Rabbit anti-Human Polyclonal (aa256-295) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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APLP2 Antibody (aa1-210, FITC) LS-C695679

Antibody:

APLP2 Rabbit anti-Human Polyclonal (aa1-210) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716

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Human APLP2 Protein (Recombinant His-T7) (aa1-210) - LS-G25683

Source:

E. coli

Tag:

His-T7

Molecular Weight:

27.0 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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Human APLP2 (Sandwich ELISA) ELISA Kit - LS-F6829

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$834

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APLP2 Antibody (aa593-621) LS-C319538

Antibody:

APLP2 Rabbit anti-Human Polyclonal (aa593-621) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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APLP2 Antibody (aa593-621, Biotin) LS-C251533

Antibody:

APLP2 Rabbit anti-Human Polyclonal (aa593-621) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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APLP2 Antibody (aa593-621, FITC) LS-C251534

Antibody:

APLP2 Rabbit anti-Human Polyclonal (aa593-621) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

APLP2 Antibody (aa593-621, APC) LS-C251532

Antibody:

APLP2 Rabbit anti-Human Polyclonal (aa593-621) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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APLP2 Antibody (aa593-621, Azide-free, HRP) LS-C251536

Antibody:

APLP2 Rabbit anti-Human Polyclonal (aa593-621) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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APLP2 Antibody (aa593-621, PE) LS-C251535

Antibody:

APLP2 Rabbit anti-Human Polyclonal (aa593-621) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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APLP2 Antibody LS-C659648

Antibody:

APLP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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APLP2 Antibody (210-290 aa, Internal) LS-C382055

Antibody:

APLP2 Rabbit anti-Human Polyclonal (210-290 aa, Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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APLP2 Antibody (C-Terminus) LS-C312807

Antibody:

APLP2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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APLP2 Antibody (aa340-450) LS-C375226

Antibody:

APLP2 Rabbit anti-Human Polyclonal (aa340-450) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

APLP2 Antibody (690-770 aa) LS-C381662

Antibody:

APLP2 Rabbit anti-Human Polyclonal (690-770 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

APLP2 Antibody (phospho-Tyr755) LS-C198636

Antibody:

APLP2 Rabbit anti-Human Polyclonal (pTyr755) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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APLP2 Antibody (Tyr274) LS-C192110

Antibody:

APLP2 Rabbit anti-Human Polyclonal (Tyr274) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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APLP2 Antibody (phospho-Tyr755) LS-C825534

Antibody:

APLP2 Rabbit anti-Human Polyclonal (pTyr755) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$357

Select

APLP2 Antibody (p755) LS-C825537

Antibody:

APLP2 Rabbit anti-Human Polyclonal (p755) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

APLP2 Antibody LS-C823797

Antibody:

APLP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

APLP2 Antibody (aa241-290) LS-C119722

Antibody:

APLP2 Rabbit anti-Human Polyclonal (aa241-290) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

APLP2 Antibody (aa714-763) LS-C198635

Antibody:

APLP2 Rabbit anti-Human Polyclonal (aa714-763) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

APLP2 Antibody LS-C804794

Antibody:

APLP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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