APH1A / APH-1

APH1A gamma secretase subunit

APH1A / APH-1 is a component of the gamma secretase complex that cleaves integral membrane proteins such as Notch receptors and beta-amyloid precursor protein. The gamma secretase complex contains this gene product, or the paralogous anterior pharynx defective 1 homolog B (APH1B), along with the presenilin, nicastrin, and presenilin enhancer-2 proteins. The precise function of this seven-transmembrane-domain protein is unknown though it is suspected of facilitating the association of nicastrin and presenilin in the gamma secretase complex as well as interacting with substrates of the gamma secretase complex prior to their proteolytic processing. Polymorphisms in a promoter region of this gene have been associated with an increased risk for developing sporadic Alzheimer's disease. Alternative splicing results in multiple protein-coding and non-protein-coding transcript variants.

☰ Filters

Products

Antibodies (30)

Proteins (5)

ELISA Kits (4)

Type

Over-Expression Lysate (4)

Primary (30)

Recombinant (1)

Sandwich (4)

Target

APH1A / APH-1 (39)

Reactivity

Human (32)

Mouse (16)

Rat (4)

Bovine (2)

Dog (2)

Hamster (1)

Horse (2)

Monkey (2)

Opossum (1)

Pig (1)

Rabbit (1)

more less

Application

IHC (11)

IHC-P (4)

WB (26)

ELISA (19)

IF (2)

Peptide-ELISA (2)

Host

rabbit (28)

goat (1)

rabbit-new zealand white (1)

Product Group

IHCPlus (3)

Isotype

IgG (24)

Clonality

polyclonal pc (30)

Format

96-Well Strip Plate (4)

APC Conjugated (2)

Azide-free (2)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (17)

Epitope

aa41-70 (7)

aa77-109 (7)

aa236-265 (1)

aa58-70 (1)

aa80-130 (1)

aa90-140 (1)

Publications

No (39)

Sample Type

Plasma (4)

Serum (4)

Tissue Homogenates (2)

Tag

6His-SUMO, N-terminus (1)

Myc-DDK (Flag) (4)

Species

Human (3)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (2)

Purification

Purified (1)

Select

IHC-plus™ APH1A / APH-1 Antibody (aa58-70) LS-B4350

(4.0) Rating

Antibody:

APH1A / APH-1 Goat anti-Human Polyclonal (aa58-70) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

Select

IHC-plus™ APH1A / APH-1 Antibody LS-B1328

(4.0) Rating

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

IHC-plus™ APH1A / APH-1 Antibody LS-B443

(4.0) Rating

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

Select

APH1A / APH-1 Antibody (aa77-109) LS-C326852

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal (aa77-109) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

APH1A / APH-1 Antibody (aa77-109, Biotin) LS-C243681

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal (aa77-109) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

APH1A / APH-1 Antibody (aa77-109, FITC) LS-C243682

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal (aa77-109) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

APH1A / APH-1 Antibody (aa77-109, Azide-free, HRP) LS-C247439

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal (aa77-109) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

APH1A / APH-1 Antibody (aa77-109, APC) LS-C243680

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal (aa77-109) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

APH1A / APH-1 Antibody (aa77-109, PE) LS-C243684

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal (aa77-109) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

APH1A / APH-1 Antibody LS-C809084

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

APH1A / APH-1 Antibody (aa77-109) LS-C100036

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal (aa77-109) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

APH1A / APH-1 Antibody LS-C677147

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

APH1A / APH-1 Antibody (aa90-140) LS-C829597

Antibody:

APH1A / APH-1 Rabbit-New Zealand White anti-Mouse Polyclonal (aa90-140) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$393

Select

APH1A / APH-1 Antibody (aa41-70) LS-C319536

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal (aa41-70) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

APH1A / APH-1 Antibody (aa41-70, Biotin) LS-C232748

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal (aa41-70) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

APH1A / APH-1 Antibody (aa41-70, FITC) LS-C232749

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal (aa41-70) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

APH1A / APH-1 Antibody (aa41-70, APC) LS-C232747

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal (aa41-70) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

APH1A / APH-1 Antibody (aa41-70, PE) LS-C232750

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal (aa41-70) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

APH1A / APH-1 Antibody (aa41-70, Azide-free, HRP) LS-C249440

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal (aa41-70) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

APH1A / APH-1 Antibody LS-C659913

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

APH1A / APH-1 Antibody LS-C764572

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

APH1A / APH-1 Antibody (aa80-130) LS-C148727

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal (aa80-130) Antibody

Reactivity:

Dog, Bovine, Opossum, Horse, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$386

Select

APH1A / APH-1 Antibody (aa41-70) LS-C159089

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal (aa41-70) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

APH1A / APH-1 Antibody LS-C749656

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

APH1A / APH-1 Antibody LS-C490100

Antibody:

APH1A / APH-1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$575

Viewing 1-25 of 39 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.