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Anti-APEX2 Antibody (aa143-171) LS-C156401

Ordering

Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular APEX2 Antibodies

Anti-APEX2 Antibody IHC-plus™ LS-B2015
Rabbit Polyclonal (IgG) to Human APEX2
Human, Monkey, Bovine, Dog, Pig, Rabbit
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-APEX2 Antibody (aa143-171, APC) LS-C275164
Rabbit Polyclonal (IgG) to Human APEX2
Human
IHC, Western blot, ELISA
APC Conjugated
Anti-APEX2 Antibody (aa504-518) LS-C312651
Rabbit Polyclonal (IgG) to Human APEX2
Human, Monkey, Mouse, Rat, Bovine, Pig, Rabbit, Sheep
IHC - Paraffin, Western blot
Unconjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human APEX2
Human
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated

Details

Human APEX2
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (1:10 - 1:50)
  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)

Specificity and Use

APEX2 antibody was raised against kLH-conjugated synthetic peptide between amino acids 143-171 from internal region of human APEX2.
LS-E9880 - Lyophilized - 100 µg - $145.00
aa143-171
Human APEX2

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About APEX2

Q9UBZ4 NM_014481 NP_055296.2

APEX2 Antibody, AP endonuclease 2 Antibody, AP endonuclease XTH2 Antibody, APEX nuclease 2 Antibody, APEX nuclease-like 2 Antibody, APEXL2 Antibody, APE2 Antibody, XTH2 Antibody

Function as a weak apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. Displays also double-stranded DNA 3'-5' exonuclease, 3'-phosphodiesterase activities.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed and paraffin-embedded human lung carcinoma reacted with APEX2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Immunofluorescence

Immunofluorescence
Immunofluorescence of U251 cells, using APEX2 Antibody. Antibody was diluted at 1:25 dilution. Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Dylight Fluor 554 (red) conjugated Phalloidin (red).

Western blot

Western blot
Western blot of APEX2 Antibody in MCF-7 cell line lysates (35 ug/lane). APEX2 (arrow) was detected using the purified antibody.

Flow Cytometry

Flow Cytometry
APEX2 Antibody flow cytometry of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Requested From: United States
Date Requested: 12/3/2016

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