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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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APC6 / CDC16 Antibody (aa87‑136) LS‑C187227
Antibody
CDC16 antibody LS-C187227 is an unconjugated rabbit polyclonal antibody to CDC16 (APC6) from human, rat, guinea pig and other species. Validated for WB.
Catalog
Size
Price
LS-C187227-50
50 µg (1 mg/ml)
Unavailable

Popular APC6 / CDC16 Products

Anti-CDC16 / Apc6 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B337 concentration 5 ug/ml.
Species: Human
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Anti-CDC16 / Apc6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4645 concentration 5 ug/ml.
Species: Human, Mouse
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IHC of paraffin-embedded human brain, using CDC16/APC6 (Phospho-Ser560) Antibody. The sample on the right was incubated with synthetic peptide.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Immunohistochemical analysis of CDC16 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX. w
Species: Human, Monkey, Pig
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay

Product Description

CDC16 antibody LS-C187227 is an unconjugated rabbit polyclonal antibody to CDC16 (APC6) from human, rat, guinea pig and other species. Validated for WB.
About APC6 / CDC16
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Q13042 NM_003903 NP_003894.3

CDC16 Antibody, ANAPC6 Antibody, APC6 Antibody, CDC16 homolog Antibody, Cyclosome subunit 6 Antibody, CDC16Hs Antibody, CUT9 Antibody


Specifications

Target
Human APC6 / CDC16
Host
Rabbit
Reactivity
Human, Rat, Guinea pig, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Monkey, Bovine, Dog, Hamster, Horse, Pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
APC6 / CDC16 antibody was raised against synthetic peptide located between aa87-136 of human CDC16 (Q13042-3). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Rat (100%); Marmoset, Hamster, Panda, Dog, Bovine, Horse, Pig (92%); Galago, Elephant, Rabbit, Guinea pig (85%).
Blocking Peptide
LS-E21674 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C187227. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa87-136
Specificity
Human APC6 / CDC16
Presentation
Lyophilized from PBS
Reconstitution
50 µl Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/20/2018

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