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Anti-APC Antibody IHC-plus™ LS-B8667

Note: This antibody replaces LS-C88800

Ordering

Wt. Vol. Conc. Price
- 250 µl 0.2 mg/ml $450
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular APC Antibodies

Anti-APC Antibody (C-Terminus) IHC-plus™ LS-B2788
Rabbit Polyclonal to Human APC
Human, Mouse, Rat
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-APC Antibody (phospho-Ser2054) LS-C351830
Rabbit Polyclonal to Human APC
Human, Monkey, Mouse, Rat, Pig
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human APC
Human, Mouse, Rat
IHC - Paraffin
Unconjugated

Details

Human APC
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Affinity purified
Unmodified

Applications

IHC - Paraffin (5 µg/ml)

Specificity and Use

APC antibody was raised against a synthetic peptide derived from C-terminus of human APC protein.
C-terminus

Packaging

10mM PBS, pH 7.6, with 0.2% BSA and 15mM sodium azide
+4°C, avoid freezing
For research use only.

About APC

P25054 NM_000038 NP_000029.2

APC Antibody, Adenomatosis polyposis coli Antibody, Adenomatous polyposis coli Antibody, BTPS2 Antibody, Deleted in polyposis 2.5 Antibody, DP2 Antibody, DP2.5 Antibody, FPC Antibody, GS Antibody, Protein APC Antibody, PPP1R46 Antibody, DP3 Antibody

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.

Immunohistochemistry

Immunohistochemistry
Anti-APC antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8667 dilution 5 ug/ml.
 

Requested From: United States
Date Requested: 12/7/2016

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