APC

Adenomatous Polyposis Coli

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.

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Products

Antibodies (69)

ELISA Kits (16)

Proteins (6)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Custom (2)

Over-Expression Lysate (2)

Primary (69)

Recombinant (4)

Sandwich (9)

Sandwich CLIA (3)

Target

APC (91)

Reactivity

Human (52)

Mouse (36)

Rat (23)

Bovine (1)

Chicken (1)

Guinea pig (1)

Monkey (4)

Pig (3)

Porcine (1)

Application

IHC (28)

IHC-Fr (1)

IHC-P (9)

WB (57)

ELISA (16)

ICC (3)

IF (8)

IP (3)

Peptide-ELISA (5)

Host

rabbit (59)

mouse (6)

goat (1)

rat (3)

Product Group

PathPlus Cancer (1)

Isotype

IgG (31)

IgG1 (5)

IgG1,k (1)

IgG2a (3)

Clonality

monoclonal mc (9)

polyclonal pc (60)

Clone

3E2 (1)

KT44 (1)

KT45 (1)

OTI1B12 (2)

OTI2B8 (2)

Format

12 x 8-Well Microstrips (4)

96-Well Microplate (2)

96-Well Strip Plate (10)

APC (2)

APC Conjugated (4)

Azide-free (1)

Biotin Conjugated (5)

Carrier-free (2)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (5)

HRP Conjugated (4)

PE Conjugated (4)

Unconjugated (43)

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Epitope

aa2634-2842 (8)

aa2636-2845 (8)

aa1148-1176 (7)

pSer2054 (6)

aa955-1382 (4)

aa2634-2843 (3)

aa1-50 (2)

1990-2070 aa (1)

2770-2850 aa, C-terminal (1)

Ab-2054 (1)

C-Terminus (1)

Gln2829 (1)

Internal (1)

Lys2050 (1)

aa1-433 (1)

aa2020-2069 (1)

aa2537-2843 (1)

aa2793-C-term (1)

aa2794-2843 (1)

aa75-125 (1)

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Publications

No (91)

Sample Type

Adherent Cell Cultures (2)

Cell Lysates (2)

Plasma (7)

Serum (7)

Tissue Homogenates (3)

Tag

GST, N-terminus (1)

His-T7 (3)

Myc-DDK (Flag) (2)

Species

Human (3)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Select

APC Antibody (2770-2850 aa, C-terminal) LS-C382049

Antibody:

APC Rabbit anti-Human Polyclonal (2770-2850 aa, C-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

Porcine APC (Sandwich ELISA) ELISA Kit - LS-F44277

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

15.63 - 1000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$863

Select

APC Antibody (aa1-50) LS-C286501

Antibody:

APC Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

Select

PathPlus™ APC Antibody (aa2794-2843) LS-B7592

Cancer

(5.0) Rating

Antibody:

APC Rabbit anti-Human Polyclonal (aa2794-2843) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$440

Select

Human APC (Sandwich ELISA) ELISA Kit - LS-F10849

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

APC Antibody (phospho-Ser2054) LS-C351830

Antibody:

APC Rabbit anti-Human Polyclonal (pSer2054) Antibody

Reactivity:

Mouse, Rat, Pig, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$315

Select

APC Antibody (C-Terminus) LS-C351831

Antibody:

APC Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Chicken, Bovine, Rat, Pig, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

Human APC (Sandwich ELISA) ELISA Kit - LS-F6613

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

Select

APC Antibody (clone 3E2) LS-C196665

Antibody:

APC Mouse anti-Human Monoclonal (3E2) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

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APC Antibody (Internal) LS-C358903

Antibody:

APC Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Pig, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

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APC Antibody (aa1148-1176) LS-C319524

Antibody:

APC Rabbit anti-Human Polyclonal (aa1148-1176) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

APC Antibody LS-C808424

Antibody:

APC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

APC Antibody (phospho-Ser2054) LS-C800672

Antibody:

APC Rabbit anti-Human Polyclonal (pSer2054) Antibody

Reactivity:

Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

APC Antibody (Gln2829) LS-C175922

Antibody:

APC Rabbit anti-Human Polyclonal (Gln2829) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

APC Antibody (aa955-1382, clone OTI2B8) LS-C338825

Antibody:

APC Mouse anti-Human Monoclonal (aa955-1382) (OTI2B8) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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APC Antibody (aa955-1382, clone OTI2B8, Carrier-free) LS-C798087

Antibody:

APC Mouse anti-Human Monoclonal (aa955-1382) (Carrier-free) (OTI2B8) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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APC Antibody LS-C834137

Antibody:

APC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

Mouse APC (Sandwich ELISA) ELISA Kit - LS-F39613

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$854

Select

Human APC Protein (Recombinant His-T7) (Ala2634-Val2843) - LS-G14885

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.2 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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Mouse APC Protein (Recombinant His-T7) (aa2636-2845) - LS-G14889

Source:

E. coli

Tag:

His-T7

Molecular Weight:

25.9 kDa

Price:

10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170

Select

Mouse APC (Sandwich ELISA) ELISA Kit - LS-F38491

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

78.13 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

APC Antibody (phospho-Ser2054) LS-C198632

Antibody:

APC Rabbit anti-Human Polyclonal (pSer2054) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

APC Antibody (1990-2070 aa) LS-C381316

Antibody:

APC Rabbit anti-Human Polyclonal (1990-2070 aa) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

APC Antibody (aa1-433) LS-C3765

Antibody:

APC Mouse anti-Human Monoclonal (aa1-433) Antibody

Reactivity:

Human

Applications:

IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

50 µg/$558

Select

APC Antibody (phospho-Ser2054) LS-C822179

Antibody:

APC Rabbit anti-Human Polyclonal (pSer2054) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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