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Anti-APC Antibody (aa2537-2843) LS-C34992

Catalog Size Price
LS-C34992-100 100 µg (0.2 mg/ml) Unavailable

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100% Guaranteed
Goat Polyclonal (IgG) to Human APC
IHC, Western blot, ELISA


Human APC
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


  • IHC (5 - 15 µg/ml)
  • Western blot (0.1 - 0.2 µg/ml)
  • ELISA (0.5 - 1 µg/ml)

Specificity and Use

APC antibody was raised against e. coli-derived rhAPC C-Terminus (aa2537-2843).
Recognize human APC C-Terminus.
Suitable for use in Western Blot, Immunohistochemistry and ELISA. Western Blot: 0.1-0.2 ug/ml, the detection limit is ~1 ng/lane under non-reducing and reducing conditions. Immunohistochemistry: 5-15 ug/ml. ELISA: 0.5-1 ug/ml, the detection limit is ~0.2 ng/well.


Lyophilized from PBS, 5% trehalose.
500 µl PBS, 40-50% glycerol
For research use only.

About APC

P25054 NM_000038 NP_000029.2

APC Antibody, Adenomatosis polyposis coli Antibody, Adenomatous polyposis coli Antibody, BTPS2 Antibody, Deleted in polyposis 2.5 Antibody, DP2 Antibody, DP2.5 Antibody, FPC Antibody, GS Antibody, Protein APC Antibody, PPP1R46 Antibody, DP3 Antibody

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.

Requested From: 
Date Requested: 5/23/2018

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