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Anti-APC Antibody (aa2537-2843) LS-C34992

Catalog Size Price
LS-C34992-100 100 µg (0.2 mg/ml) Unavailable

Related Products

74 APC Antibodies

Most Popular APC Antibodies

Anti-APC Antibody (C-Terminus) IHC-plus™ LS-B2788
Rabbit Polyclonal to Human APC
Human, Mouse, Rat
IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Anti-APC antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2788 concentration 10 ug/ml.
Anti-APC Antibody (phospho-Ser2054) LS-C351830
Rabbit Polyclonal to Human APC
Human, Monkey, Mouse, Rat, Pig
Western blot
Unconjugated
Western blot analysis of APC (pS2054) expression in HeLa (A); Caco2 (B); SW480 (C); MCF7 (D); SP2/0 (E); PC12 (F) whole cell lysates.
Anti-APC Antibody (aa2770-2850) LS-C382049
Rabbit Polyclonal (IgG) to Human APC
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot, ELISA
Unconjugated
Western blot of APC antibody
Anti-APC Antibody (aa2636-2845, Biotin) LS-C686975
Rabbit Polyclonal (IgG) to Mouse APC
Mouse
IHC, Western blot
Biotin Conjugated
Western blot of recombinant APC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-APC Antibody (aa2634-2842, Biotin) LS-C686980
Rabbit Polyclonal (IgG) to Rat APC
Rat
IHC, Western blot
Biotin Conjugated
Western blot of recombinant APC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

100% Guaranteed
Goat Polyclonal (IgG) to Human APC
Human
IHC, Western blot, ELISA
Unconjugated

Details

Human APC
Goat
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC (5 - 15 µg/ml)
  • Western blot (0.1 - 0.2 µg/ml)
  • ELISA (0.5 - 1 µg/ml)

Specificity and Use

APC antibody was raised against e. coli-derived rhAPC C-Terminus (aa2537-2843).
aa2537-2843
Recognize human APC C-Terminus.
Suitable for use in Western Blot, Immunohistochemistry and ELISA. Western Blot: 0.1-0.2 ug/ml, the detection limit is ~1 ng/lane under non-reducing and reducing conditions. Immunohistochemistry: 5-15 ug/ml. ELISA: 0.5-1 ug/ml, the detection limit is ~0.2 ng/well.

Packaging

Lyophilized from PBS, 5% trehalose.
500 µl PBS, 40-50% glycerol
For research use only.

About APC

P25054 NM_000038 NP_000029.2

APC Antibody, Adenomatosis polyposis coli Antibody, Adenomatous polyposis coli Antibody, BTPS2 Antibody, Deleted in polyposis 2.5 Antibody, DP2 Antibody, DP2.5 Antibody, FPC Antibody, GS Antibody, Protein APC Antibody, PPP1R46 Antibody, DP3 Antibody

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.

Requested From: 
Date Requested: 5/23/2018

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