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Anti-APAF1 / APAF-1 Antibody (N-Terminus) LS-C284

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml Unavailable

Most Popular APAF1 / APAF-1 Antibodies

Anti-APAF1 / APAF-1 Antibody (aa12-28) IHC-plus™ LS-B743
Rabbit Polyclonal to Human APAF1 / APAF-1
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-APAF1 / APAF-1 Antibody (C-Terminus) IHC-plus™ LS-B3340
Rabbit Polyclonal to Human APAF1 / APAF-1
Human, Mouse, Rat
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-APAF1 / APAF-1 Antibody LS-C148201
Rabbit Polyclonal to Human APAF1 / APAF-1
Human, Mouse, Rat, Gerbil
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image

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Rabbit Polyclonal to Human APAF1 / APAF-1
Human, Mouse, Rat
Western blot
Unconjugated

Details

Human APAF1 / APAF-1
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot
IHC - Paraffin

Specificity and Use

APAF1 / APAF-1 antibody was raised against synthetic peptide from human APAF1 / APAF-1.
LS-E29868 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-C284. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
N-Terminus
peptide corresponding to amino acids near the amino terminus of human Apaf-1 The sequences of the immunogenic peptide are identical between human and mouse

Packaging

PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About APAF1 / APAF-1

O14727 NM_013229 NP_037361.1

APAF1 Antibody, APAF-1 Antibody, CED4 Antibody, KIAA0413 Antibody

Apaf1 has been described as the core of the apoptosome. Deficiency in murine Apaf1 leads to embryonic lethality with a phenotype affecting many aspects of developmental apoptosis. In the developing brain, Apaf1 is a death regulator of the neuronal founder cells. Combined intercrosses of mouse lines mutant for members of the mitochondrial death pathway are providing us with some clues about the relative regulation existing among neuronal cell populations.

Immunofluorescence

Immunofluorescence
Immunofluorescence of Apaf1 in K562 cells with Apaf1 antibody at 10 ug/ml.

Western blot

Western blot
Western blot of Apaf1 in K562 cell lysate with Apaf1 antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.

Requested From: 
Date Requested: 3/25/2017

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