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Anti-APAF1 / APAF-1 Antibody (aa12-28) IHC-plus™ LS-B743

Note: This antibody replaces LS-C26610


Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular APAF1 / APAF-1 Antibodies

Anti-APAF1 / APAF-1 Antibody (C-Terminus, clone 2E10) LS-C53478
Mouse Monoclonal [clone 2E10] to Human APAF1 / APAF-1
Human, Mouse, Rat
IHC, Western blot
Immunohistochemistry Image
Anti-APAF1 / APAF-1 Antibody (aa1-464, clone 2E12, Low Endotoxin) IHC-plus™ LS-B12884
Rat Monoclonal [clone 2E12] (IgG2a,k) to Human APAF1 / APAF-1
IHC - Paraffin, ICC, Western blot, Immunoprecipitation, ELISA
Unconjugated, Low Endotoxin
Immunohistochemistry - Paraffin Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human APAF1 / APAF-1
Human, Mouse, Rat
IHC - Paraffin, Western blot


Human APAF1 / APAF-1
Human, Mouse, Rat (tested or 100% immunogen sequence identity)


  • IHC - Paraffin (20 µg/ml)
  • Western blot

Specificity and Use

APAF1 / APAF-1 antibody was raised against synthetic peptide corresponding to amino acids 12 to 28 of the human Apaf-1 protein. The immunogen sequence is identical in human and mouse.
Amino acids 12 to 28 of human APAF1
Immunohistochemistry: LS-B743 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B743 was determined to be 20 ng/ml.


PBS, 0.02% sodium azide.
+4°C, avoid freezing
For research use only.

About APAF1 / APAF-1

O14727 NM_013229 NP_037361.1

APAF1 Antibody, APAF-1 Antibody, CED4 Antibody, KIAA0413 Antibody

Apaf1 has been described as the core of the apoptosome. Deficiency in murine Apaf1 leads to embryonic lethality with a phenotype affecting many aspects of developmental apoptosis. In the developing brain, Apaf1 is a death regulator of the neuronal founder cells. Combined intercrosses of mouse lines mutant for members of the mitochondrial death pathway are providing us with some clues about the relative regulation existing among neuronal cell populations.


Anti-APAF1 / APAF-1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B743 concentration 20 ug/ml.


Anti-APAF1 / APAF-1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B743 concentration 20 ug/ml.

Requested From: United States
Date Requested: 10/22/2016

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