Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 2F10] (IgG2a) to Human ANPEP / CD13
IHC - Paraffin, Western blot
Mouse Monoclonal [clone WM-15 (WM15)] (IgG1,k) to Human ANPEP / CD13
Human ANPEP / CD13
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [WM-15 (WM15)]
IHC - Paraffin
Specificity and Use
ANPEP / CD13 antibody was raised against human ANPEP
The WM-15 (WM15) antibody has been tested by flow cytometric analysis of lysed whole blood. This can be used at less than or equal to 1 ug per test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
PBS, pH 7.2, 150 mM sodium chloride, 0.09% sodium azide
Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May play a critical role in the pathogenesis of cholesterol gallstone disease. May be involved in the metabolism of regulatory peptides of diverse cell types, responsible for the processing of peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines.
Staining of normal human peripheral blood cells with granulocyte gates were used for analysis.
Staining of normal human peripheral blood cells with 0.5 ug of purified mouse IgG1 isotype control (open histogram) or 0.5 ug of purified WM-15 (colored histogram) followed by FITC anti-mouse IgG. Cells in the monocyte gates were used for analysis.