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Anti-AML1 / RUNX1 Antibody (N-Terminus) IHC-plus™ LS-B998

Note: This antibody replaces LS-C30175

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $450
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular AML1 / RUNX1 Antibodies

Anti-AML1 / RUNX1 Antibody (N-Terminus) IHC-plus™ LS-B998
Rabbit Polyclonal to Human AML1 / RUNX1
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken, Zebrafish
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-AML1 / RUNX1 Antibody (clone 4E7) IHC-plus™ LS-B5383
Mouse Monoclonal [clone 4E7] (IgG2b,k) to Human AML1 / RUNX1
Human, Mouse
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-AML1 / RUNX1 Antibody (Internal, clone 15B) LS-C191744
Rabbit Polyclonal [clone 15B] (IgG) to Human AML1 / RUNX1
Human, Mouse
IHC - Paraffin, ICC, Western blot, ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human AML1 / RUNX1
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken, Zebrafish
IHC - Paraffin, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human AML1 / RUNX1
Rabbit
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken, Zebrafish (tested or 100% immunogen sequence identity)
Xenopus (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

AML1 / RUNX1 antibody was raised against synthetic peptide from N-Terminus of human RUNX1 (Q01196). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Guinea pig, Chicken (100%); Opossum, Zebra finch, Xenopus (92%); Zebrafish (85%).
LS-E13657 - Lyophilized - 100 µg - $145.00
N-Terminus
Human RUNX1
Immunohistochemistry: LS-B998 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B998 was determined to be 5 ug/ml.

Packaging

Lyophilized from PBS with 2% sucrose
After adding water, will consist of PBS buffer with 2% sucrose
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About AML1 / RUNX1

Q01196 NM_001754 NP_001745.2

RUNX1 Antibody, AMLCR1 Antibody, Aml1 oncogene Antibody, AML1 Antibody, AML1-EVI-1 Antibody, CBF-alpha-2 Antibody, CBFA2 Antibody, Acute myeloid leukemia 1 Antibody, EVI-1 Antibody, PEBP2A2 Antibody, PEA2-alpha B Antibody, AML1-EVI-1 fusion protein Antibody, Oncogene AML-1 Antibody, PEBP2-alpha B Antibody, PEBP2aB Antibody

CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter.

Immunohistochemistry

Immunohistochemistry
Anti-RUNX1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B998 concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
RUNX1 antibody LS-B998 Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
A: Marker, B: Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/8/2016

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