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Anti-ALPL / Alkaline Phosphatase Antibody (HRP) LS-C55817

Note: This antibody replaces LS-C74835

Ordering

Wt. Vol. Conc. Price
- 1000 µl 1 mg/ml $325
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ALPL / Alkaline Phosphatase Antibodies

Anti-ALPL / Alkaline Phosphatase Antibody (clone TRA-2-49/6E) LS-C38190
Mouse Monoclonal [clone TRA-2-49/6E] (IgG1) to Human ALPL / Alkaline Phosphatase
Human, Monkey, Cat, Pig, Rabbit
Immunofluorescence, Immunoprecipitation, Flow Cytometry
Unconjugated
Anti-ALPL / Alkaline Phosphatase Antibody IHC-plus™ LS-B3666
Mouse Monoclonal (IgG1) to Human ALPL / Alkaline Phosphatase
Human, Bovine
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Sheep Polyclonal to Human ALPL / Alkaline Phosphatase
Human
ELISA (applications tested for the base form of this product only)
HRP Conjugated

Details

Human ALPL / Alkaline Phosphatase
Sheep
Human (tested or 100% immunogen sequence identity)
Polyclonal
Horseradish Peroxidase. Also available Unconjugated.
Affinity purified
Unmodified

Applications

  • ELISA
  • (applications tested for the base form of this product only)

Specificity and Use

ALPL / Alkaline Phosphatase antibody was raised against alkaline phosphatase from human bone.
Recognizes human bone alkaline phosphatase (BAP), a membrane-bound hydrolase enzyme expressed by osteoblast cells. Alkaline phosphatase (AP) is a ubiquitously expressed enzyme which removes phosphate groups from target molecules, including DNA, RNA and alkaloids, under alkaline conditions, and is present at higher concentrations in the placenta (placental AP), intestines (intestinal AP) and liver/bone/kidney (tissue non-specific AP). Although the exact biochemical function of BAP is uncertain, measurement of the serum levels of BAP can be used as a biochemical indicator of bone turnover. Conditions which present with a decrease in the level of BAP (hypophosphatasemia) include the inherited bone-deforming disorder hypophosphatasia and osteoporosis, whilst an increase in BAP (hyperphosphatasemia) is associated with Pageta€™s disease, bone fractures and osteosarcomas.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, pH 7.4, 0.01% Thimerosal.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About ALPL / Alkaline Phosphatase

P05186 NM_000478 NP_000469.3

ALPL Antibody, Alkaline phosphomonoesterase Antibody, AP-TNAP Antibody, Alkaline phosphatase liver Antibody, APTNAP Antibody, Glycerophosphatase Antibody, Tissue-nonspecific ALP Antibody, TNAP Antibody, HOPS Antibody, Liver alkaline phosphatase Antibody, TNSALP Antibody

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme.

Requested From: United States
Date Requested: 12/4/2016

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