Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
ALPL / Alkaline Phosphatase
alkaline phosphatase, liver/bone/kidney
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described.
| Gene Name: | alkaline phosphatase, liver/bone/kidney |
| Synonyms: | ALPL, Alkaline phosphomonoesterase, AP-TNAP, Alkaline phosphatase liver, APTNAP, Glycerophosphatase, Tissue-nonspecific ALP, TNAP, HOPS, Liver alkaline phosphatase, TNSALP |
| Target Sequences: | NM_000478 NP_000469.3 P05186 |
Publications (1)
1
Collagen-Hydroxyapatite Scaffolds Induce Human Adipose Derived Stem Cells Osteogenic Differentiation In Vitro. Calabrese G, Giuffrida R, Fabbi C, Figallo E, Lo Furno D, Gulino R, Colarossi C, Fullone F, Giuffrida R, Parenti R, Memeo L, Forte S. PloS one. 2016 11:e0151181. (WB, ELISA, IHC-Fr; Bovine, Human)
[Full Text Article]
[PubMed:26982592]
[PMC:PMC4794180]
Related Antibodies: LS-C98218.
☰ Filters
Products
Antibodies
(96)
ELISA Kits
(25)
Proteins
(17)
Type
Competitive EIA
(6)
Custom
(1)
Over-Expression Lysate
(6)
Primary
(96)
Recombinant
(11)
Sandwich
(15)
Sandwich CLIA
(3)
Target
ALPL / Alkaline Phosphatase
(138)
Reactivity
Human
(89)
Mouse
(46)
Rat
(22)
Bovine
(5)
Canine
(1)
Cat
(6)
Chicken
(1)
Monkey
(7)
Pig
(15)
Rabbit
(7)
Application
IHC
(17)
IHC-P
(15)
WB
(71)
Flo
(11)
ELISA
(43)
ICC
(6)
IF
(8)
IP
(9)
Peptide-ELISA
(2)
RNAi
(1)
Host
rabbit
(60)
mouse
(34)
goat
(1)
rat
(1)
Product Group
IHCPlus
(4)
Isotype
IgG
(37)
IgG1
(29)
IgG1,k
(3)
IgG2a
(1)
IgG2b,k
(1)
Clonality
monoclonal mc
(34)
polyclonal pc
(62)
Clone
2F4
(2)
4H1
(1)
OTI3A1
(1)
TRA-2-49/6E
(1)
V17.1
(3)
Format
12 x 8-Well Microstrips
(4)
96-Well Strip Plate
(21)
APC
(2)
APC Conjugated
(5)
Azide-free
(1)
Biotin Conjugated
(11)
BSA-free
(1)
Cy3 Conjugated
(2)
Cy7 Conjugated
(2)
FITC Conjugated
(11)
HRP Conjugated
(11)
Magnetic beads Conjugated
(1)
PE Conjugated
(9)
Ready-to-Use
(1)
Sepharose Conjugated
(1)
Unconjugated
(43)
Epitope
aa18-335
(16)
aa3-32
(7)
N-Terminus
(4)
aa18-502
(2)
180-260 aa, Internal
(1)
Internal
(1)
aa 28-501
(1)
aa1-359
(1)
aa18-32
(1)
aa188-237
(1)
aa20-270
(1)
aa21-35
(1)
aa28-501
(1)
aa31-45
(1)
aa42-53
(1)
Publications
No
(137)
Yes
(1)
Sample Type
Cell Culture Supernatants
(1)
Cell Supernatant
(1)
Plasma
(24)
Serum
(24)
Tissue Homogenates
(8)
Tag
6His, C-terminus
(2)
6His-SUMO, N-terminus
(1)
GST
(1)
GST, N-terminus
(1)
His
(4)
His-T7
(1)
Myc-DDK (Flag)
(7)
Species
Human
(11)
Mouse
(2)
Rat
(1)
Source
293T Cells
(3)
E. coli
(5)
HEK 293 Cells
(4)
Human Cells
(2)
Mammalian Cells
(1)
Wheat Germ Extract
(2)
Purification
Purified
(2)
Low Endotoxin Level
Low endotoxin level
(4)
ALPL / Alkaline Phosphatase Mouse anti-Human Monoclonal (aa18-502) (2F4) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ALPL / Alkaline Phosphatase Mouse anti-Human Monoclonal Antibody
Bovine, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$575
ALPL / Alkaline Phosphatase Mouse anti-Human Monoclonal (FITC) Antibody
Bovine, Human
ELISA, WB
FITC Conjugated
100 µl/$951
ALPL / Alkaline Phosphatase Mouse anti-Human Monoclonal (TRA-2-49/6E) Antibody
Rabbit, Pig, Cat, Human, Monkey
Flo, IF, IP
Unconjugated
100 µg/$880
ALPL / Alkaline Phosphatase Mouse anti-Human Monoclonal (HRP) Antibody
Rabbit, Pig, Cat, Human, Monkey
Flo, ICC, IF, IP
HRP Conjugated
100 µl/$1,094
ALPL / Alkaline Phosphatase Mouse anti-Human Monoclonal (Biotin) Antibody
Rabbit, Pig, Cat, Human, Monkey
Flo, ICC, IF, IP
Biotin Conjugated
100 µl/$1,094
ALPL / Alkaline Phosphatase Mouse anti-Human Monoclonal (FITC) Antibody
Rabbit, Pig, Cat, Human, Monkey
Flo, ICC, IF, IP
FITC Conjugated
100 µl/$1,094
ALPL / Alkaline Phosphatase Mouse anti-Human Monoclonal (APC) Antibody
Rabbit, Pig, Cat, Human, Monkey
Flo, ICC, IF, IP
APC Conjugated
100 µl/$1,094
ALPL / Alkaline Phosphatase Mouse anti-Human Monoclonal (PE) Antibody
Rabbit, Pig, Cat, Human, Monkey
Flo, ICC, IF, IP
PE Conjugated
100 µl/$1,094
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$818
Sandwich
96-Well Strip Plate
Human
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
Sandwich
12 x 8-Well Microstrips
Human
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
ALPL / Alkaline Phosphatase Rabbit anti-Human Polyclonal (aa3-32) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
ALPL / Alkaline Phosphatase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$380
ALPL / Alkaline Phosphatase Rabbit anti-Human Polyclonal (N-Terminus) (Magnetic beads) Antibody
Mouse, Rat, Human
IP
Magnetic beads Conjugated
100 µg/$399
Competitive EIA
96-Well Strip Plate
Human
3.12 - 200 U/l
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
ALPL / Alkaline Phosphatase Rabbit anti-Human Polyclonal (aa28-501) (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
ALPL / Alkaline Phosphatase Mouse anti-Human Monoclonal (4H1) Antibody
Human
ELISA, RNAi, WB
Unconjugated
100 µg/$423
ALPL / Alkaline Phosphatase Rat anti-Human Monoclonal (aa18-502) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$896
ALPL / Alkaline Phosphatase Rabbit anti-Human Polyclonal (aa3-32) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
ALPL / Alkaline Phosphatase Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
200 µg/$677
ALPL / Alkaline Phosphatase Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
100 µl/$951
ALPL / Alkaline Phosphatase Rabbit anti-Human Polyclonal (aa1-359) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
ALPL / Alkaline Phosphatase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$331
ALPL / Alkaline Phosphatase Mouse anti-Human Monoclonal (2F4) Antibody
Human
Flo, IHC, WB
Unconjugated
100 µg/$503
Viewing 1-25
of 138
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
