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Anti-ALK2 / ACVR1 Antibody (aa496-509) IHC-plus™ LS-B2010

Note: This antibody replaces LS-C19345, LS-C63637

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Most Popular ALK2 / ACVR1 Antibodies

Anti-ALK2 / ACVR1 Antibody (aa496-509) IHC-plus™ LS-B2010
Rabbit Polyclonal to Human ALK2 / ACVR1
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Xenopus
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-ALK2 / ACVR1 Antibody (Extracellular Domain) LS-C122594
Goat Polyclonal (IgG) to Human ALK2 / ACVR1
Human
IHC, Western blot, Flow Cytometry, ELISA
Unconjugated
Anti-ALK2 / ACVR1 Antibody (aa80-129) IHC-plus™ LS-B6835
Rabbit Polyclonal (IgG) to Human ALK2 / ACVR1
Human, Monkey, Mouse, Bovine, Goat, Guinea pig, Horse, Pig
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human ALK2 / ACVR1
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Xenopus
IHC - Paraffin, Western blot
Unconjugated

Details

Human ALK2 / ACVR1
Rabbit
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Xenopus (tested or 100% immunogen sequence identity)
Chicken (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • Western blot (3 - 5 µg/ml)

Specificity and Use

ALK2 / ACVR1 antibody was raised against a synthetic peptide corresponding to amino acids 496-509 (TKIDNSLDKLKTDC) of amino acids 475-525 of human ACVR1, GenBank NP 001096. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig, Xenopus (100%); Opossum, Turkey, Chicken, Platypus, Salmon (93%); Stickleback, Pufferfish (86%).
aa496-509
In human kidney, additional bands are seen at approximately 27 and 14 kD.
Immunohistochemistry: LS-B2010 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2010 was determined to be 10 ug/ml.

Packaging

PBS, 0.2% gelatin, 0.05% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About ALK2 / ACVR1

Q04771 NM_001105 NP_001096.1

ACVR1 Antibody, Activin A receptor type I Antibody, Activin A receptor, type I Antibody, ACTR-I Antibody, ActRIA Antibody, ACVR1A Antibody, ALK2 Antibody, Activin receptor-like kinase 2 Antibody, Activin receptor type-1 Antibody, ACTRI Antibody, ACVRLK2 Antibody, ALK-2 Antibody, Activin receptor type I Antibody, Actr1 Antibody, FOP Antibody, Hydroxyalkyl-protein kinase Antibody, SKR1 Antibody, TSRI Antibody, TSR-I Antibody, Tsk7L Antibody

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors.

Immunohistochemistry

Immunohistochemistry
Anti-ACVR1 antibody IHC of human skeletal muscle, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2010 concentration 10 ug/ml.

Western blot

Western blot
Western blot of ACVR1 in mouse kidney lysate using antibody at 5 ug/ml

Requested From: United States
Date Requested: 12/10/2016

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