ABCD1 antibody LS-C11823 is an unconjugated mouse monoclonal antibody to human ABCD1 (ALDP). Validated for ELISA, ICC, IHC and WB.
Human ALDP / ABCD1
(tested or 100% immunogen sequence identity)
- IHC (1:500 - 1:5000)
- ICC (1:500 - 1:5000)
- Western blot (1:500 - 1:5000)
- ELISA (1:500 - 1:5000)
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ALDP / ABCD1 antibody was raised against aLDP1 fragment from aa 279 to 482 as a fusion protein.
Human ALDP. No cross-reactivity with mouse ALDRP, PMP70. Cross-reactivity to an unidentified 80kD MW protein is present in lymphoblastoid cells, but not in several other cells or tissues tested.
ELISA: 1:500-1:5000. Western Blot: 1:500-1:5000. Immunohistochemistry: 1:500-1:5000. Immunocytochemistry: 1:500-1:5000. Can be used to analyze ALDP protein in cells and tissues from normal individuals, or from patients with adrenoleukodystrophy (ALD) or Zellweger syndrome and related peroxisomal diseases, and provides an excellent marker for peroxisomes (Mosser et al. 1994). About 70% of ALD male patients have no detectable ALDP in fibroblasts or leukocytes. A similar proportion of carrier females may show mosaicism for the presence or absence of ALDP.
Ascites without preservative.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.