Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
The aldehyde dehydrogenases (ALDH) are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The ALDH7 gene spans about 20 kb of genomic DNA and is composed of 9 coding exons. The gene encodes a single transcript of 2.8 kb which is highly expressed in kidney and lung. ALDH7 is highly homologous with ALDH8 and the two genes show 86% identity in their open reading frames.
Formalin-fixed and paraffin-embedded human lung carcinoma reacted with ALDH3B1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of ALDH3B1 Antibody in MDA-MB231 cell line lysates (35 ug/lane). ALDH3B1 (arrow) was detected using the purified antibody.
Western blot of ALDH3B1 (arrow) using rabbit polyclonal ALDH3B1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ALDH3B1 gene.
Requested From: United States
Date Requested: 1/22/2017