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| Catalog Number | Size | Price |
|---|---|---|
| LS-B10149-200 | 200 µl | $460 |
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PathPlus™ Monoclonal Mouse anti‑Human ALDH1A1 / ALDH1 Antibody (IHC, IF, WB) LS‑B10149
PathPlus™ Monoclonal Mouse anti‑Human ALDH1A1 / ALDH1 Antibody (IHC, IF, WB) LS‑B10149
Note: This antibody replaces LS-C156250
Antibody:
ALDH1A1 / ALDH1 Mouse anti-Human Monoclonal Antibody
Application:
IHC-P, IF, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
ALDH1A1 / ALDH1 Mouse anti-Human Monoclonal Antibody
Application:
IHC-P, IF, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
ALDH1A1 (ALDH1) is an aldehyde dehydrogenase and is involved in alcohol metabolism in the liver. It also plays a role in retinol metabolism, converting or oxidizing retinaldehyde to retinoic acid, and it is thought to modulate metabolic responses to a high-fat diet. ALDH1A1 is overexpressed in various cancers, and it is associated with worse prognosis in lung cancer, esophageal squamous cell carcinoma, breast cancer, and stomach cancer, and also chemo-resistance in ovarian cancer. In immunohistochemistry of normal tissue, ALDH1A1 has secreted and cytoplasmic positivity in various tissues including the liver, gallbladder, gastrointestinal tissue, kidney, thyroid, lung, reproductive tissues, adipose tissue, and brain.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804; FASEB J. 2017 Jan; 31(1): 203–211, PMID: 27729412; Oncotarget. 2016 Mar 8; 7(10): 11018–11032, PMID: 26783961
Target
Human ALDH1A1 / ALDH1
Synonyms
ALDH1A1 | Acetaldehyde dehydrogenase 1 | ALDH class 1 | ALDC | Aldehyde dehydrogenase 1 | ALDH-E1 | ALDH1 | ALDH11 | PUMB1 | RALDH 1 | RALDH1 | ALHDII | Retinal dehydrogenase 1 | Retinaldehyde dehydrogenase 1
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
- IHC - Paraffin (1:50)
- Immunofluorescence (1:10 - 1:50)
- Western blot (1:500 - 1:1000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.09% Sodium Azide
Storage
Maintain refrigerated at 2°C to 8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ALDH1A1 / ALDH1
Validation
Anti-ALDH1A1 / ALDH1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ALDH1A1 / ALDH1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ ALDH1A1 / ALDH1 Antibody for IHC, IF/Immunofluorescence, WB/Western LS-B10149 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (1)
BRCA1 mutation influences progesterone response in human benign mammary organoids. Batzaya Davaadelger, Mi-Ran Choi, Hari Singhal, Susan E Clare, Seema A Khan, J Julie Kim. Breast cancer research : BCR. 2019 Nov;21:124.
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Species:
Human
Applications:
IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Species:
Human, Bovine, Sheep
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/25/2024
Date Requested: 4/25/2024
