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ALCAM / CD166
activated leukocyte cell adhesion molecule
Activated leukocyte cell adhesion molecule (ALCAM)/cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. Homophilic (ALCAM-ALCAM) adhesion was shown to play important roles in tight cell-to-cell interaction and regulation of stem cell differentiation. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells involved in dynamic growth and/or migration, including neural development, branching organ development, hematopoiesis, immune response and tumor progression.
| Gene Name: | activated leukocyte cell adhesion molecule |
| Synonyms: | ALCAM, CD166 antigen, MEMD, CD166 |
| Target Sequences: | NM_001627 NP_001618.2 Q13740 |
Publications (4)
1
GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC. Fekete N, Rojewski MT, Fürst D, Kreja L, Ignatius A, Dausend J, Schrezenmeier H. PloS one. 2012 7:e43255. (Flo; Human)
[Full Text Article]
[PubMed:22905242]
Related Antibodies: LS-C84947.
2
A novel molecular magnetic resonance imaging agent targeting activated leukocyte cell adhesion molecule as demonstrated in mouse brain metastasis models. Niloufar Zarghami, Manuel Sarmiento Soto, Francisco Perez-Balderas, Alexandre A Khrapitchev, Christina Simoglou Karali, Vanessa A Johanssen, Olaf Ansorge, James R Larkin, Nicola R Sibson. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2020 November;271678X20968943. [Full Text Article]
[PubMed:33153376]
[PMC:PMC8217895]
Related Antibodies: LS-C292613.
3
Amniotic stromal stem cell-loaded hydrogel repairs cardiac tissue in infarcted rat hearts via paracrine mediators. Kashif Khan, Georges Makhoul, Bin Yu, Ghulam Jalani, Ida Derish, Alissa K Rutman, Marta Cerruti, Adel Schwertani, Renzo Cecere. Journal of tissue engineering and regenerative medicine. 2022 Feburary;16:110-127. [Full Text Article]
[PubMed:34726328]
Related Antibodies: LS-C35861.
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Antibodies
(126)
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Type
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(126)
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(18)
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(24)
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(2)
Target
ALCAM / CD166
(175)
Reactivity
Human
(90)
Mouse
(34)
Rat
(29)
Bovine
(8)
Chicken
(2)
Cow
(8)
Crab-eating macaque
(3)
Cynomolgus
(3)
Dog
(9)
Monkey
(1)
Porcine
(1)
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(10)
Application
IHC
(21)
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(1)
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(11)
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(87)
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(30)
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(1)
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(10)
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rabbit
(74)
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(42)
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(2)
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(8)
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(2)
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(27)
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(21)
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(5)
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monoclonal mc
(45)
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(81)
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018
(3)
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(1)
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(14)
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(7)
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(7)
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(15)
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(8)
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(10)
Preservative Free
(1)
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(2)
Unconjugated
(54)
Epitope
aa28-527
(43)
aa208-476
(8)
aa225-478
(8)
Amino Acid: 405-524
(3)
Extracellular Domain
(3)
aa48-216
(2)
481-530 aa, C-terminal
(1)
C-Terminus
(1)
aa58-87
(1)
Publications
No
(171)
Yes
(4)
Sample Type
Cell Culture Supernatants
(9)
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(4)
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(1)
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(25)
Serum
(25)
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(7)
Tag
6His-SUMO, N-terminus
(1)
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(1)
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(4)
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(1)
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(1)
His
(6)
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(1)
His-Fc
(1)
His-T7
(2)
Species
Bovine
(1)
Dog
(1)
Human
(7)
Mouse
(5)
Rabbit
(1)
Rat
(3)
Source
E. coli
(7)
HEK 293 Cells
(1)
Human Cells
(6)
Mammalian Cells
(2)
Wheat Germ Extract
(2)
Purification
Purified
(5)
Low Endotoxin Level
Low endotoxin level
(9)
ALCAM / CD166 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
Block, Flo
Biotin Conjugated
100 µg/$626
ALCAM / CD166 Mouse anti-Human Monoclonal (FITC) (3A6) Antibody
Human
Flo, Func
FITC Conjugated
120 Tests/$446
ALCAM / CD166 Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-Fr
Unconjugated
100 µg/$558
ALCAM / CD166 Mouse anti-Human Monoclonal (FITC) (3A6) Antibody
Human
Flo
FITC Conjugated
120 Tests/$752
ALCAM / CD166 Mouse anti-Human Monoclonal (3F8B12) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$440
ALCAM / CD166 Mouse anti-Human Monoclonal (10F1G12) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$460
ALCAM / CD166 Mouse anti-Human Monoclonal (aa48-216) (8E12C7) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
ALCAM / CD166 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo
FITC Conjugated
120 Tests/$626
ALCAM / CD166 Guinea pig anti-Rabbit Polyclonal (aa225-478) Antibody
Rabbit
ICC, IP, WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
ALCAM / CD166 Mouse anti-Human Monoclonal (3A6) Antibody
Human
Flo
Unconjugated
100 µg/$648
ALCAM / CD166 Rabbit anti-Mouse Polyclonal (aa28-527) Antibody
Mouse, Rat, Human
ICC, IP, WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
ALCAM / CD166 Mouse anti-Human Monoclonal (Azide-free) (3A6) Antibody
Human
Flo, Func
Unconjugated, Azide-free
100 µg/$411
ALCAM / CD166 Mouse anti-Human Monoclonal (aa48-216) (4H9A5) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$459
ALCAM / CD166 Rabbit anti-Human Polyclonal (aa58-87) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
ALCAM / CD166 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
ALCAM / CD166 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
ALCAM / CD166 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$332
ALCAM / CD166 Rabbit anti-Crab-eating macaque Monoclonal (Preservative Free) (018) Antibody
Crab-eating macaque
ELISA, Flo
Unconjugated, Preservative Free
100 µl/$412
ALCAM / CD166 Mouse anti-Human Monoclonal (3D9F1) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
ALCAM / CD166 Mouse anti-Human Monoclonal (2F1B12) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
ALCAM / CD166 Rabbit anti-Crab-eating macaque Monoclonal (FITC) (018) Antibody
Crab-eating macaque
Flo
FITC Conjugated
25 Tests/$278; 100 Tests/$346
ALCAM / CD166 Rabbit anti-Crab-eating macaque Monoclonal (PE) (018) Antibody
Crab-eating macaque
Flo
PE Conjugated
25 Tests/$278; 100 Tests/$376
ALCAM / CD166 Rabbit anti-Cow Polyclonal (aa28-527) (PE) Antibody
Mouse, Bovine, Cow
WB
PE Conjugated
100 µl/$423; 200 µl/$513; 500 µl/$901; 1 ml/$1,067; 2 ml/$1,412; 5 ml/$2,647
ALCAM / CD166 Mouse anti-Human Monoclonal Antibody
Human
Flo, ICC, IF
Unconjugated
100 µl/$412
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of 175
product results
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