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AKR1C4 / Chlordecone Reductase

aldo-keto reductase family 1, member C4

Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.

Gene Name: aldo-keto reductase family 1, member C4
Synonyms: AKR1C4, 3-alpha-HSD, 3-alpha-HSD1, Chlordecone reductase, CDR, CHDR, DD-4, Dihydrodiol dehydrogenase 4, C11, DD4, HAKRA
Target Sequences: NM_001818 NP_001809.3 P17516

☰ Filters
Antibodies (27)
Proteins (8)
ELISA Kits (4)
Custom (1)
Over-Expression Lysate (2)
Primary (27)
Recombinant (6)
Sandwich (3)
AKR1C4 / Chlordecone Reductase (39)
Human (31)
Mouse (1)
Rat (2)
IHC (7)
IHC-P (6)
WB (23)
ELISA (13)
IF (2)
IP (1)
Peptide-ELISA (2)
rabbit (24)
mouse (2)
goat (1)
Product Group
IHCPlus (2)
IgG (21)
IgG1,k (1)
monoclonal mc (1)
polyclonal pc (26)
2C11 (1)
96-Well Microplate (1)
96-Well Strip Plate (2)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (2)
Unconjugated (17)
aa11-39 (7)
aa1-323 (2)
aa1-217 (1)
aa2-14 (1)
No (39)
Cell Culture Supernatants (1)
EDTA Plasma (1)
Heparin Plasma (1)
Plasma (2)
Serum (3)
Tissue Homogenates (1)
6His, N-terminus (2)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (7)
293T Cells (1)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (4)
Low endotoxin level (2)
Biologically active (1)
AKR1C4 / Chlordecone Reductase Protein
Select
E. coli
His
Biologically active
100 µg/$361; 500 µg/$739; 20 µg/$261
AKR1C4 / Chlordecone Reductase Antibody - Anti-AKR1C4 antibody IHC of human tonsil, squamous epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
AKR1C4 / Chlordecone Reductase Mouse anti-Human Monoclonal (2C11) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
AKR1C4 / Chlordecone Reductase Antibody - Anti-AKR1C4 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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AKR1C4 / Chlordecone Reductase Goat anti-Human Polyclonal (aa2-14) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
AKR1C4 / Chlordecone Reductase Antibody - Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
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AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal (aa1-323) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
AKR1C4 / Chlordecone Reductase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$341
AKR1C4 / Chlordecone Reductase Antibody - Immunohistochemistry of paraffin-embedded human liver using antibody at 1:100 dilution.
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal (aa1-323) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
AKR1C4 / Chlordecone Reductase Antibody - IHC of paraffin-embedded gastric ca using AKR1C4 antibody at 1:100 dilution.
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal (aa1-217) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$450
AKR1C4 / Chlordecone Reductase Antibody - 1:100 staining human lymph node tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
AKR1C4 / Chlordecone Reductase Antibody - Western blot analysis of extracts of various cell lines.
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal (aa11-39) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal (aa11-39) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal (aa11-39) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal (aa11-39) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal (aa11-39) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal (aa11-39) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
AKR1C4 / Chlordecone Reductase Antibody - AKR1C4 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The AKR1C4 antibody detected the AKR1C4 protein (arrow).
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal (aa11-39) Antibody
Human
WB
Unconjugated
400 µl/$393
AKR1C4 / Chlordecone Reductase Antibody - Immunochemical staining of human AKR1C4 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Select
AKR1C4 / Chlordecone Reductase Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
Select
AKR1C4 / Chlordecone Reductase Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-25 of 39 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).