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Anti-AKR1C4 / Chlordecone Reductase Antibody (clone 2C11) IHC-plus™ LS-B5390

Note: This antibody replaces LS-C133118
Catalog Size Price
LS-B5390-50 50 µg (0.5 mg/ml) Unavailable

Most Popular AKR1C4 / Chlordecone Reductase Antibodies

Anti-AKR1C4 / Chlordecone Reductase Antibody (aa2-14) IHC-plus™ LS-B2759
Goat Polyclonal to Human AKR1C4 / Chlordecone Reductase
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-AKR1C4 / Chlordecone Reductase Antibody (clone 2C11) IHC-plus™ LS-B5390
Mouse Monoclonal [clone 2C11] (IgG1,k) to Human AKR1C4 / Chlordecone Reductase
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-AKR1C4 / Chlordecone Reductase Antibody (aa10-39, Biotin) LS-C212651
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
Western blot, ELISA
Biotin Conjugated
Anti-AKR1C4 / Chlordecone Reductase Antibody LS-C401755
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human, Mouse
IHC, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-AKR1C4 / Chlordecone Reductase Antibody LS-C405059
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human, Mouse
IHC, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed
Mouse Monoclonal [clone 2C11] (IgG1,k) to Human AKR1C4 / Chlordecone Reductase
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated

Details

Human AKR1C4 / Chlordecone Reductase
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [2C11]
Unconjugated
Purified from ascites by Protein A
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Immunofluorescence (15 µg/ml)
  • Western blot
  • ELISA

Specificity and Use

AKR1C4 (AAH20744, 1 a.a. ~ 324 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Human AKR1C4
Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Western Blot: Cell lysate, Transfected lysate, Recombinant protein.

Packaging

PBS, pH 7.2
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About AKR1C4 / Chlordecone Reductase

P17516 NM_001818 NP_001809.3

AKR1C4 Antibody, 3-alpha-HSD Antibody, 3-alpha-HSD1 Antibody, Chlordecone reductase Antibody, CDR Antibody, CHDR Antibody, DD-4 Antibody, Dihydrodiol dehydrogenase 4 Antibody, C11 Antibody, DD4 Antibody, HAKRA Antibody

Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.

Immunohistochemistry

Immunohistochemistry
Anti-AKR1C4 antibody IHC of human tonsil, squamous epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5390 concentration 5 ug/ml.

Immunofluorescence

Immunofluorescence
Immunofluorescence of monoclonal antibody to AKR1C4 on HepG2 cell. [antibody concentration 15 ug/ml]

Western blot

Western blot
AKR1C4 monoclonal antibody (M01), clone 2C11 Western blot of AKR1C4 expression in MCF-7.

Western blot

Western blot
Western blot of AKR1C4 expression in transfected 293T cell line by AKR1C4 monoclonal antibody (M01), clone 2C11.

Requested From: 
Date Requested: 10/18/2017

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