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Anti-AKR1C4 / Chlordecone Reductase Antibody (aa1-217) LS-C185549

Ordering

Wt. Vol. Conc. Price
- 100 µl 0.83 mg/ml $335
Inquire for larger quantities

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206-374-1102
866-206-6909
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Most Popular AKR1C4 / Chlordecone Reductase Antibodies

Anti-AKR1C4 / Chlordecone Reductase Antibody (aa2-14) IHC-plus™ LS-B2759
Goat Polyclonal to Human AKR1C4 / Chlordecone Reductase
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-AKR1C4 / Chlordecone Reductase Antibody (clone 2C11) IHC-plus™ LS-B5390
Mouse Monoclonal [clone 2C11] (IgG1,k) to Human AKR1C4 / Chlordecone Reductase
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-AKR1C4 / Chlordecone Reductase Antibody (aa10-39, Biotin) LS-C212651
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
Western blot, ELISA
Biotin Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human AKR1C4 / Chlordecone Reductase
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human AKR1C4 / Chlordecone Reductase
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (1:100 - 1:1000)
  • Western blot (1:500 - 1:3000)

Specificity and Use

AKR1C4 / Chlordecone Reductase antibody was raised against recombinant fragment corresponding to a region within amino acids 1 and 217 of HSD3a (SwissProt P17516).
aa1-217
Human AKR1C4
IHC-paraffin: Suggested antigen retrieval using heat mediated 10 mM Citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 8.0).

Packaging

0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
For research use only.

About AKR1C4 / Chlordecone Reductase

P17516 NM_001818 NP_001809.3

AKR1C4 Antibody, 3-alpha-HSD Antibody, 3-alpha-HSD1 Antibody, Chlordecone reductase Antibody, CDR Antibody, CHDR Antibody, DD-4 Antibody, Dihydrodiol dehydrogenase 4 Antibody, C11 Antibody, DD4 Antibody, HAKRA Antibody

Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.

Immunohistochemistry

Immunohistochemistry
IHC of paraffin-embedded gastric ca using AKR1C4 antibody at 1:100 dilution.

Western blot

Western blot
Sample (30 ug of whole cell lysate). A: Hela. 10% SDS PAGE. HSD3a antibody. AKR1C4 antibody diluted at 1:1000.

Requested From: United States
Date Requested: 12/5/2016

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