AIRE

autoimmune regulator

The AIRE gene function is not well defined, however the protein does contain zinc finger motifs suggestive of a transcription factor. The protein (isoform 1) is localized to both the nucleus and cytoplasm. Three splice variant mRNAs products have been described [1]. The longer AIRE-1 mRNA appears to be more abundant and includes exons 1 through 14. Splice variant AIRE-2 includes a portion of the non-coding region of exon 1, an alternatively spliced longer exon 8, plus exons 9 through 14. Variant AIRE-3 includes the same exon 1-8-9 sequences as found in AIRE-2 but utilizes additional alternative splicing in exon 10 that shifts the reading frame such that a stop codon in exon 12 is utilized. The resulting protein products of these splice variants are differ significantly. Defects in this gene cause the autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).

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Products

Antibodies (59)

ELISA Kits (16)

Proteins (5)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Competitive EIA (1)

Custom (1)

Over-Expression Lysate (4)

Primary (59)

Recombinant (1)

Sandwich (11)

Sandwich CLIA (1)

Target

AIRE (80)

Reactivity

Human (66)

Mouse (28)

Rat (10)

Bovine (6)

Chicken (1)

Chimpanzee (6)

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Host

rabbit (52)

goat (5)

rabbit-new zealand white (2)

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Unconjugated (36)

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aa76-125 (8)

aa64-92 (7)

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100-180 aa (2)

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aa100-150 (1)

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Yes (1)

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Myc-DDK (Flag) (5)

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HEK 293 Cells (3)

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IHC-plus™ AIRE Antibody (aa534-545) LS-B1740

(4.0) Rating

Antibody:

AIRE Goat anti-Human Polyclonal (aa534-545) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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IHC-plus™ AIRE Antibody (aa102-115) LS-B1741

(4.0) Rating

Antibody:

AIRE Goat anti-Human Polyclonal (aa102-115) Antibody

Reactivity:

Dog, Rat, Hamster, Horse, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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AIRE Antibody (N-Terminus) LS-B11873

(4.0) Rating

(1) Publication(s)

Antibody:

AIRE Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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AIRE Antibody (N-Terminus, HRP) LS-C428304

Antibody:

AIRE Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Rat, Horse, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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AIRE Antibody (N-Terminus, Biotin) LS-C428302

Antibody:

AIRE Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Rat, Horse, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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AIRE Antibody (N-Terminus, FITC) LS-C428303

Antibody:

AIRE Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Rat, Horse, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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IHC-plus™ AIRE Antibody LS-B11914

(4.0) Rating

Antibody:

AIRE Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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AIRE Antibody LS-C662452

Antibody:

AIRE Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Flo, ICC, IHC, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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AIRE Antibody LS-C677097

Antibody:

AIRE Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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Human AIRE (Sandwich ELISA) ELISA Kit - LS-F20949

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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AIRE Antibody LS-C416026

Antibody:

AIRE Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

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AIRE Antibody (Internal) LS-C353900

Antibody:

AIRE Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$299

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AIRE Antibody (aa64-92) LS-C319394

Antibody:

AIRE Rabbit anti-Human Polyclonal (aa64-92) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

200 µl/$734

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AIRE Antibody (aa64-92, Biotin) LS-C251081

Antibody:

AIRE Rabbit anti-Human Polyclonal (aa64-92) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, ICC, IF, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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AIRE Antibody (aa64-92, FITC) LS-C251082

Antibody:

AIRE Rabbit anti-Human Polyclonal (aa64-92) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, ICC, IF, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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AIRE Antibody (aa64-92, APC) LS-C251080

Antibody:

AIRE Rabbit anti-Human Polyclonal (aa64-92) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, ICC, IF, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

AIRE Antibody (aa64-92, PE) LS-C251085

Antibody:

AIRE Rabbit anti-Human Polyclonal (aa64-92) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, ICC, IF, WB

Format:

PE Conjugated

Price:

200 µl/$952

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AIRE Antibody (aa64-92, Azide-free, HRP) LS-C251083

Antibody:

AIRE Rabbit anti-Human Polyclonal (aa64-92) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, ICC, IF, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

AIRE Antibody (60-140 aa, Internal) LS-C381955

Antibody:

AIRE Rabbit anti-Human Polyclonal (60-140 aa, Internal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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AIRE Antibody LS-C659233

Antibody:

AIRE Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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AIRE Antibody LS-C822464

Antibody:

AIRE Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

AIRE Antibody (aa91-140) LS-C118687

Antibody:

AIRE Rabbit anti-Human Polyclonal (aa91-140) Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

AIRE Antibody LS-C417288

Antibody:

AIRE Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

Select

AIRE Antibody LS-C763937

Antibody:

AIRE Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

AIRE Antibody (aa64-92) LS-C156200

Antibody:

AIRE Rabbit anti-Human Polyclonal (aa64-92) Antibody

Reactivity:

Mouse, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

400 µl/$393

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