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AIMP1 / EMAP II
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.
| Gene Name: | aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 |
| Synonyms: | AIMP1, EMAP II, EMAPII, EMAP-2, HLD3, p43, EMAP2, SCYE1 |
| Target Sequences: | NM_004757 NP_004748.2 Q12904 |
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AIMP1 / EMAP II
(86)
Reactivity
Human
(59)
Mouse
(35)
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(17)
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(5)
Cat
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(5)
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Horse
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Monkey
(7)
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(53)
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rabbit
(53)
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IgG
(26)
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monoclonal mc
(5)
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(58)
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05
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546-2
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(1)
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(1)
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(1)
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(6)
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(1)
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(7)
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(5)
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Preservative Free
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(38)
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(8)
aa2-310
(8)
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(4)
aa31-80
(4)
91-140 aa, Internal
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
Publications
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(86)
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(1)
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(1)
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(7)
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(7)
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(4)
Tag
6His-SUMO, N-terminus
(1)
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(1)
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(6)
Species
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(9)
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(2)
Source
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(3)
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(7)
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(3)
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(1)
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(4)
Low Endotoxin Level
Low endotoxin level
(1)
Biologically Active
Biologically active
(1)
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$902
Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$923
AIMP1 / EMAP II Goat anti-Human Polyclonal (aa27-38) Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
AIMP1 / EMAP II Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
AIMP1 / EMAP II Goat anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
AIMP1 / EMAP II Goat anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
AIMP1 / EMAP II Mouse anti-Human Monoclonal (AT6D10) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
~18 kDa
20 µg/$432; 1 mg/$6,427
AIMP1 / EMAP II Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, ICC, IF, IHC-P, IP, WB
Unconjugated, Preservative Free
100 µl/$412
AIMP1 / EMAP II Goat anti-Human Polyclonal (aa137-149) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
AIMP1 / EMAP II Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
AIMP1 / EMAP II Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
AIMP1 / EMAP II Rabbit anti-Human Polyclonal (aa1-263) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
AIMP1 / EMAP II Rabbit anti-Human Polyclonal (aa25-180) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
AIMP1 / EMAP II Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
AIMP1 / EMAP II Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
AIMP1 / EMAP II Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
AIMP1 / EMAP II Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
AIMP1 / EMAP II Rabbit anti-Human Polyclonal (aa242-268) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
AIMP1 / EMAP II Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
AIMP1 / EMAP II Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
100 µl/$412
AIMP1 / EMAP II Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IP, WB
Unconjugated
100 µl/$412
AIMP1 / EMAP II Rabbit anti-Human Polyclonal (aa262-312) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
AIMP1 / EMAP II Rabbit anti-Human Polyclonal (aa720-800) Antibody
Mouse, Dog, Guinea pig, Bovine, Pig, Cat, Horse, Hamster-Chinese, Rat, Opossum, Primate, Human
IHC, IHC-P, WB
Unconjugated
0.1 mg/$386
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