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AICDA / AID
activation-induced cytidine deaminase
Activation-induced cytidine deaminase (AICDA) was initially discovered as a homolog of the apolipoprotein B RNA-editing cytidine deaminase 1 (APOBEC1) that showed cytidine deaminase properties in stimulated B cell lines. AICDA is necessary for somatic hypermutation and class switch recombination in B cells, but inappropriate or dysregulated expression AID is often found in tumors and B cell neoplasms. Although AICDA is structurally and functionally similar to the APOBEC proteins, it appears unlikely that AID deaminates dC to dU residues in HIV cDNA as does APOBEC3G.
| Gene Name: | activation-induced cytidine deaminase |
| Synonyms: | AICDA, AID, ARP2, CDA2, Cytidine aminohydrolase, HIGM2 |
| Target Sequences: | NM_020661 NP_065712.1 Q9GZX7 |
Publications (3)
1
Primary central nervous system lymphoma: tumor-related clones exist in the blood and bone marrow with evidence for separate development. McCann KJ, Ashton-Key M, Smith K, Stevenson FK, Ottensmeier CH. Blood. 2009 113:4677-80. (IHC; Human)
[PubMed:19096008]
Related Antibodies: LS-B16.
2
Activation-induced cytidine deaminase expression in diffuse large B-cell lymphoma with a paracortical growth pattern: a lymphoma of possible interfollicular large B-cell origin. Aguilera NS, Auerbach A, Barekman CL, Lichy J, Abbondanzo SL. Archives of pathology & laboratory medicine. 2010 134:449-56. (IHC-P; Human)
[PubMed:20196672]
Related Antibodies: LS-C34861.
3
The BRCT domain of PARP-1 is required for immunoglobulin gene conversion. Paddock MN, Buelow BD, Takeda S, Scharenberg AM. PLoS biology. 2010 8:e1000428. (WB; Chicken)
[Full Text Article]
[PubMed:20652015]
[PMC:PMC2907289]
Related Antibodies: LS-C34861.
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AICDA / AID Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
AICDA / AID Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$565
AICDA / AID Rabbit anti-Human Polyclonal Antibody
IHC, IHC-P
Unconjugated
50 µl/$460
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
AICDA / AID Rat anti-Human Monoclonal (Asp191) Antibody
Human
WB
Unconjugated
100 µl/$702
AICDA / AID Mouse anti-Human Monoclonal Antibody
Mouse, Human
IP, WB
Unconjugated
100 µl/$702
AICDA / AID Rabbit anti-Human Monoclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$688
AICDA / AID Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
AICDA / AID Goat anti-Human Polyclonal (aa8-19) Antibody
Hamster, Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
AICDA / AID Rat anti-Human Monoclonal (EK2-5G9) Antibody
Human
ELISA, Flo, IHC-P, WB
Unconjugated
50 µg/$310
AICDA / AID Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
AICDA / AID Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$557
AICDA / AID Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
ELISA, ICC, WB
Unconjugated
100 µg/$649
AICDA / AID Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
0.1 mg/$379
AICDA / AID Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
AICDA / AID Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
AICDA / AID Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
AICDA / AID Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
AICDA / AID Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
AICDA / AID Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
AICDA / AID Rabbit anti-Human Polyclonal (Biotin) Antibody
Rabbit, Mouse, Dog, Rat, Pig, Horse, Human
IHC
Biotin Conjugated
100 µl/$469
AICDA / AID Rabbit anti-Human Polyclonal (HRP) Antibody
Rabbit, Mouse, Dog, Rat, Pig, Horse, Human
IHC
HRP Conjugated
100 µl/$469
AICDA / AID Rabbit anti-Human Polyclonal (FITC) Antibody
Rabbit, Mouse, Dog, Rat, Pig, Horse, Human
IHC
FITC Conjugated
100 µl/$469
AICDA / AID Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
AICDA / AID Rabbit anti-Human Polyclonal Antibody
Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
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