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Anti-AHR Antibody (aa78-127) LS-C31439

Catalog Size Price
LS-C31439-100 100 µg (1 mg/ml) Unavailable

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100% Guaranteed
Rabbit Polyclonal (IgG) to Human AHR
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Details

Human AHR
Rabbit
Human, Mouse, Rat, Bovine, Dog, Rabbit (tested or 100% immunogen sequence identity)
Monkey, Bat, Guinea pig (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Protein A purified
Unmodified

Applications

  • IHC
  • IHC - Paraffin
  • Western blot (2.5 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

AHR antibody was raised against synthetic peptide located between aa78-127 of human AHR (P35869, NP_001612). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%); Monkey, Bat, Guinea pig (92%); Gibbon, Galago, Marmoset, Hamster, Elephant, Dog, Bovine (85%); Mouse (78%); Rat (76%).
LS-E11267 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C31439. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa78-127
Human AHR

Packaging

Lyophilized from PBS with 2% sucrose
100 µl After adding water, will consist of PBS buffer with 2% sucrose
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
For research use only.

About AHR

P35869 NM_001621 NP_001612.1

AHR Antibody, Ah receptor Antibody, AH-receptor Antibody, Aryl hydrocarbon receptor Antibody, BHLHe76 Antibody, Aromatic hydrocarbon receptor Antibody

Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues.

Immunohistochemistry

AHR antibody LS-C31439 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
AHR antibody LS-C31439 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 5/22/2018

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