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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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AGTR1 / AT1 Receptor Antibody (N‑Terminus) LS‑C11853
AT1 Receptor antibody LS-C11853 is an unconjugated rabbit polyclonal antibody to AT1 Receptor (AGTR1) from human, mouse, rat and other species. Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C11853-100
100 µl
$725

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Product Description

AT1 Receptor antibody LS-C11853 is an unconjugated rabbit polyclonal antibody to AT1 Receptor (AGTR1) from human, mouse, rat and other species. Validated for ELISA and WB.
About AGTR1 / AT1 Receptor
Type 1 Angiotensin Receptors (AT1A and AT1B) mediate the major cardiovascular effects of angiotensin II, controlling blood pressure and volume by regulating cell growth, vascular contraction, inflammatory responses, and salt and water retention. P30556 NM_000685 NP_000676.1

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Specifications

Target
Rat AGTR1 / AT1 Receptor
Host
Rabbit
Reactivity
Rat, Human, Mouse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Dog, Sheep (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • Western blot (1:1000 - 1:5000)
  • ELISA (1:10000 - 1:100000)
Immunogen
Synthetic peptide 10aa sequence the N-terminus, extracellular of rat AT II (1) (KLH coupled).
Epitope
N-Terminus
Specificity
Recognizes rat Angiotensin II type 1 Receptor. Sequence is the same in all AT II receptor isoforms (Type 1a, 1b and 1c). No sequence homology with other G-protein coupled receptors. Species sequence homology: Mouse, human, porcine, sheep, canine, chimpanzee and rabbit: 100%.
Usage
Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence.
Presentation
PBS, 0.05% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/18/2018

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