Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Involvement of functional autoantibodies against vascular receptors in systemic sclerosis. Riemekasten G, Philippe A, N[Character e4]ther M, Slowinski T, M[Character fc]ller DN, Heidecke H, Matucci-Cerinic M, Czirj[Character e1]k L, Lukitsch I, Becker M, Kill A, van Laar JM, Catar R, Luft FC, Burmester GR, Hegner B, Dragun D. Annals of the rheumatic diseases. 2011 Mar;70:530-6. [Full Text Article]
Type 1 Angiotensin Receptors (AT1A and AT1B) mediate the major cardiovascular effects of angiotensin II, controlling blood pressure and volume by regulating cell growth, vascular contraction, inflammatory responses, and salt and water retention.