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Anti-AGRP Antibody (aa119-132) LS-C54458

Ordering

Wt. Vol. Conc. Price
100 µg - - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular AGRP Antibodies

Anti-AGRP Antibody LS-C150318
Rabbit Polyclonal (IgG) to Human AGRP
Human, Mouse, Rat
ELISA, Dot Blot
Unconjugated
Anti-AGRP Antibody (clone 82815) LS-C125014
Mouse Monoclonal [clone 82815] (IgG1) to Human AGRP
Human
Western blot, ELISA
Unconjugated
Anti-AGRP Antibody LS-C150146
Goat Polyclonal (IgG) to Mouse AGRP
Mouse
IHC, Western blot
Unconjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human AGRP
Human, Monkey, Bat, Horse
ELISA
Unconjugated

Details

Human AGRP
Goat
Human, Monkey, Bat, Horse (tested or 100% immunogen sequence identity)
Dog, Pig (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

ELISA (1:32000)
IHC - Paraffin

Specificity and Use

AGRP antibody was raised against synthetic peptide CRKLGTAMNPCSRT from the C-terminus of human AGRP (NP_001129.1; NP_015531.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Panda, Bat, Horse (100%); Dog, Pig (93%); Mouse, Hamster, Elephant, Zebu, Bovine (86%).
LS-E25861 - Lyophilized - 100 µg - $145.00
aa119-132
Human AGRP. This antibody is expected to recognise both reported isoforms (as represented by NP_001129; NP_015531)
Preliminary experiments gave bands at approx 45kDa and 24kDa in Human Brain lysates after 0.1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 14.4kDa according to NP_001129.1and NP_015531.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About AGRP

O00253 NM_001138 NP_001129.1

AGRP Antibody, Agouti (mouse) related protein Antibody, Agouti-related protein Antibody, Agouti-related transcript Antibody, AGRT Antibody, ASIP2 Antibody

Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity.

Requested From: United States
Date Requested: 12/8/2016

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