Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone AGR3.4] (IgG1) to Human AGR2/AGR3
IHC - Paraffin, ICC, Western blot
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [AGR3.4]
Protein A purified
IHC - Paraffin (5 µg/ml)
ICC (1 µg/ml)
Western blot (1 µg/ml)
Specificity and Use
AGR2/AGR3 antibody was raised against purified human AGR3 protein.
The antibody AGR3.4 recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kD); secreted cytoplasmic proteins which can serve as markers of carcinogenesis.
Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody,
15 mM sodium azide, 0.2% BSA, PBS
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.