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AGL

amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase

Glycogen debranching enzyme is involved in glycogen degradation and has two independent catalytic activities: a 4-alpha-glucotransferase activity (EC 2.4.1.25) and a amylo-1,6-glucosidase activity (EC 3.4.1.33). Both activities occur at different sites on the single polypeptide chain. Mutations in this gene cause glycogen storage disease. A wide range of clinical and enzymatic variability occurs in glycogen debrancher deficiency, some of which may be due to tissue-specific alternative splicing. Six splice variants that differ in the 5' end have been identified in liver and muscle tissue. Variants 1, 5, and 6 are present in both liver and muscle, whereas variants 2, 3, and 4 occur in muscle. Variants 1 through 4 encode identical proteins (isoform 1) that include 27 N-terminal amino acids not found in splice variants 5 and 6. Variants 5 and 6 encode different amino-terminal ends of 10 and 11 amino acids in protein isoforms 2 and 3, respectively, with the remainder of the peptide identical to that of isoforms 1.

Gene Name: amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
Synonyms: AGL, GDE, Glycogen debrancher, Glycogen debranching enzyme
Target Sequences: NM_000028 NP_000019.2 P35573

☰ Filters
Antibodies (15)
Proteins (12)
ELISA Kits (3)
Custom (1)
Over-Expression Lysate (8)
Primary (15)
Recombinant (4)
Sandwich (2)
AGL (30)
Human (17)
Mouse (1)
Dog (1)
WB (9)
ELISA (12)
ICC (10)
IF (13)
rabbit (14)
mouse (1)
IgG (14)
polyclonal pc (15)
96-Well Microplate (1)
96-Well Strip Plate (2)
APC Conjugated (2)
Azide-free (2)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (2)
Unconjugated (5)
aa1479-1510 (7)
N-Terminus (6)
No (30)
Cell Lysates (1)
Plasma (1)
Serum (1)
Tissue Homogenates (1)
His-T7, N-terminus (1)
Myc-DDK (Flag) (11)
Human (8)
293T Cells (4)
E. coli (1)
HEK 293 Cells (7)
Purified (1)
AGL Antibody - Confocal immunofluorescence of AGL Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).
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AGL Rabbit anti-Human Polyclonal (aa1479-1510) Antibody
Human
IF, WB
Unconjugated
400 µl/$393
AGL Antibody - Western blot analysis of extracts of various cell lines, using AGL antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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AGL Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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AGL Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IF
Unconjugated
200 µl/$734
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AGL Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human
ELISA, ICC, IF
Biotin Conjugated
200 µl/$952
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AGL Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Human
ELISA, ICC, IF
FITC Conjugated
200 µl/$952
Select
AGL Rabbit anti-Human Polyclonal (N-Terminus) (APC) Antibody
Human
ELISA, ICC, IF
APC Conjugated
200 µl/$952
Select
AGL Rabbit anti-Human Polyclonal (N-Terminus) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF
HRP Conjugated, Azide-free
200 µl/$952
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AGL Rabbit anti-Human Polyclonal (N-Terminus) (PE) Antibody
Human
ELISA, ICC, IF
PE Conjugated
200 µl/$952
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AGL Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
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AGL Rabbit anti-Human Polyclonal (aa1479-1510) Antibody
Human
ELISA, IF, WB
Unconjugated
200 µl/$734
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AGL Rabbit anti-Human Polyclonal (aa1479-1510) (Biotin) Antibody
Human
ELISA, ICC, IF, WB
Biotin Conjugated
200 µl/$952
Select
AGL Rabbit anti-Human Polyclonal (aa1479-1510) (FITC) Antibody
Human
ELISA, ICC, IF, WB
FITC Conjugated
200 µl/$952
Select
AGL Rabbit anti-Human Polyclonal (aa1479-1510) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
AGL Rabbit anti-Human Polyclonal (aa1479-1510) (PE) Antibody
Human
ELISA, ICC, IF, WB
PE Conjugated
200 µl/$952
Select
AGL Rabbit anti-Human Polyclonal (aa1479-1510) (APC) Antibody
Human
ELISA, ICC, IF, WB
APC Conjugated
200 µl/$952
AGL ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
AGL ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$929
AGL ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
AGL Protein - Purified recombinant protein AGL was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
174.6 kDa
20 µg/$1,107
AGL Protein - Purified recombinant protein AGL was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
174.6 kDa
20 µg/$1,107
AGL Protein - Purified recombinant protein AGL was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
174.6 kDa
20 µg/$1,107
AGL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
174.6 kDa
20 µg/$150
AGL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
174.6 kDa
20 µg/$150
AGL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
174.6 kDa
20 µg/$215
AGL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
174.6 kDa
20 µg/$215
Viewing 1-25 of 30 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).