AGER / RAGE

advanced glycosylation end product-specific receptor

Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides.

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Products

Antibodies (116)

ELISA Kits (43)

Proteins (15)

Type

Competitive EIA (2)

Custom (4)

Development Kit (1)

Over-Expression Lysate (4)

Primary (116)

Recombinant (11)

Sandwich (32)

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Target

AGER / RAGE (174)

Reactivity

Human (106)

Mouse (68)

Rat (44)

Bovine (9)

Chicken (1)

Chimpanzee (3)

Gibbon (3)

Guinea pig (5)

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Peptide-ELISA (2)

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rabbit (97)

mouse (15)

goat (1)

rat (1)

sheep (2)

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IgG (57)

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IgG2a,k (7)

Clonality

monoclonal mc (16)

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175409 (1)

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Format

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C-Terminus (11)

aa10-188 (8)

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Internal (1)

aa174-192 (1)

aa23-342 (1)

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Publications

No (172)

Yes (2)

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Cell Culture Supernatants (14)

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Serum (38)

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IHC-plus™ AGER / RAGE Antibody (aa23-405, clone 1C1) LS-B6042

(5.0) Rating

(1) Publication(s)

Antibody:

AGER / RAGE Mouse anti-Human Monoclonal (aa23-405) (1C1) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$485

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IHC-plus™ AGER / RAGE Antibody (clone DD/A11, Cy3) LS-B4813

(4.0) Rating

Antibody:

AGER / RAGE Mouse anti-Human Monoclonal (Cy3) ( DD/A11) Antibody

Reactivity:

Bovine, Human

Applications:

ELISA, ICC, IHC, IHC-P, WB

Format:

Cy3 Conjugated

Price:

50 µg/$485

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IHC-plus™ AGER / RAGE Antibody (aa350-400) LS-B8004

(4.0) Rating

Antibody:

AGER / RAGE Rabbit anti-Human Polyclonal (aa350-400) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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AGER / RAGE Antibody (aa24-52) LS-C156148

Antibody:

AGER / RAGE Rabbit anti-Human Polyclonal (aa24-52) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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AGER / RAGE Antibody (aa24-52) LS-C319374

Antibody:

AGER / RAGE Rabbit anti-Human Polyclonal (aa24-52) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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AGER / RAGE Antibody (aa24-52, FITC) LS-C212627

Antibody:

AGER / RAGE Rabbit anti-Human Polyclonal (aa24-52) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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AGER / RAGE Antibody (aa24-52, APC) LS-C212626

(4.2) Rating

(3) Publication(s)

Antibody:

AGER / RAGE Rabbit anti-Human Polyclonal (aa24-52) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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AGER / RAGE Antibody (aa24-52, PE) LS-C212633

Antibody:

AGER / RAGE Rabbit anti-Human Polyclonal (aa24-52) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• FITC
• APC
• PE

• Unconjugated
• FITC
• APC
• More...
  • PE

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Monkey AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F40878

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

78.13 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Sheep AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F40881

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

39.063 - 2500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$760

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Rat AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F521

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.411 - 300 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$588

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AGER / RAGE Antibody (N-Terminus) LS-C171832

Antibody:

AGER / RAGE Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$380

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AGER / RAGE Antibody (clone 1C1) LS-C196627

Antibody:

AGER / RAGE Mouse anti-Human Monoclonal (1C1) Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$423

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AGER / RAGE Antibody (Extracellular Domain, clone 175409) LS-C75327

Antibody:

AGER / RAGE Rat anti-Mouse Monoclonal (Extracellular Domain) (175409) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

500 µg/$1,089

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Porcine AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F40879

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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AGER / RAGE Antibody (FITC) LS-C539007

Antibody:

AGER / RAGE Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Mouse, Bovine, Human

Applications:

ELISA, ICC, IHC, WB

Format:

FITC Conjugated

Price:

100 µl/$1,094

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AGER / RAGE Antibody (Biotin) LS-C529077

Antibody:

AGER / RAGE Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Mouse, Bovine, Human

Applications:

ELISA, ICC, IHC, WB

Format:

Biotin Conjugated

Price:

100 µl/$1,094

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AGER / RAGE Antibody (aa23-342, HRP) LS-C212320

Antibody:

AGER / RAGE Rabbit anti-Human Polyclonal (aa23-342) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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AGER / RAGE Antibody (FITC) LS-C212317

Antibody:

AGER / RAGE Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• HRP
• FITC

• HRP
• FITC

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AGER / RAGE Antibody LS-C801415

Antibody:

AGER / RAGE Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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AGER / RAGE Antibody (C-Terminus) LS-C31853

Antibody:

AGER / RAGE Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

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AGER / RAGE Antibody (aa29-59) LS-C328472

Antibody:

AGER / RAGE Rabbit anti-Human Polyclonal (aa29-59) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

200 µl/$734

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AGER / RAGE Antibody LS-C131267

Antibody:

AGER / RAGE Sheep anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$628

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AGER / RAGE Antibody (Extracellular Domain, APC) LS-C519028

Antibody:

AGER / RAGE Mouse anti-Human Monoclonal (Extracellular Domain) (APC) Antibody

Reactivity:

Mouse, Bovine, Human

Applications:

ELISA, ICC, IHC, WB

Format:

APC Conjugated

Price:

100 µl/$1,094

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AGER / RAGE Antibody (Extracellular Domain, PE) LS-C657156

Antibody:

AGER / RAGE Mouse anti-Human Monoclonal (Extracellular Domain) (PE) Antibody

Reactivity:

Mouse, Bovine, Human

Applications:

ELISA, ICC, IHC, WB

Format:

PE Conjugated

Price:

100 µl/$1,094

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