Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Western blot (1:2000)
Specificity and Use
AGE antibody was raised against glycated modified protein.
Recognizes a variety of advanced glycated end product (AGE) epitopes. Glycation is the post-translational modification of proteins, linking a reducing sugar to an amino group on a protein. AGEs are thought to be involved in structural and functional alterations of proteins observed in aging and diabetes. AGEs recognized by AHP1250 include carboxymethyllysine and pentosidine. Increases in pentosidine levels are associated with aging, diabetes, cataracts, renal diseases, chronic rheumatoid arthritis, photoaged skin and Alzheimer's disease. Carboxymethyllysine is involved in uracemia.
Serum, 0.1% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.