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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ADRBK1 / GRK2 Antibody (N‑Terminus) LS‑C97473
GRK2 antibody LS-C97473 is an unconjugated rabbit polyclonal antibody to human GRK2 (ADRBK1). Validated for WB.
Catalog
Size
Price
LS-C97473-50
50 µg
Unavailable

Popular ADRBK1 / GRK2 Products

Antibody
Species: Human, Rat, Mammal
Applications: IHC, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GRK2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Immunohistochemical analysis of GRK2 (pS29) staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Species: Human, Mouse, Rat, Bovine
Applications: IHC, IHC - Paraffin, Western blot

Product Description

GRK2 antibody LS-C97473 is an unconjugated rabbit polyclonal antibody to human GRK2 (ADRBK1). Validated for WB.
About ADRBK1 / GRK2
Beta-adrenergic receptor kinase (ADRBK1) phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. ADRBK1 is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. The ADRBK1 gene spans approximately 23 kb and is composed of 21 exons. P25098 NM_001619 NP_001610.2

ADRBK1 Antibody, BARK1 Antibody, Beta-ARK-1 Antibody, BETA-ARK1 Antibody, BARK Antibody, Betaark1 Antibody, GRK2 Antibody


Specifications

Target
Human ADRBK1 / GRK2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Ammonium sulfate precipitation
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Immunogen
ADRBK1 / GRK2 antibody was raised against kLH conjugated synthetic peptide selected from the N-terminal region of human ADRBK1.
Epitope
N-Terminus
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of ADRBK1 (arrow) using rabbit polyclonal ADRBK1 Antibody (N-term) LS-C97473. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ADRBK1 gene (Lane 2).
Western blot of ADRBK1 (arrow) using rabbit polyclonal ADRBK1 Antibody (N-term) LS-C97473. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ADRBK1 gene (Lane 2).

Western blot

Western blot of ADRBK1 Antibody (N-term) LS-C97473 in MDA-MB231 cell line lysates (35 ug/lane). ADRBK1 (arrow) was detected using the purified Pab.
Western blot of ADRBK1 Antibody (N-term) LS-C97473 in MDA-MB231 cell line lysates (35 ug/lane). ADRBK1 (arrow) was detected using the purified Pab.

Western blot

Western blot of ADRBK1 (arrow) using rabbit polyclonal ADRBK1 Antibody (N-term) LS-C97473. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ADRBK1 gene (Lane 2).
Western blot of ADRBK1 (arrow) using rabbit polyclonal ADRBK1 Antibody (N-term) LS-C97473. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ADRBK1 gene (Lane 2).

Western blot

Western blot of ADRBK1 Antibody (N-term) LS-C97473 in MDA-MB231 cell line lysates (35 ug/lane). ADRBK1 (arrow) was detected using the purified Pab.
Western blot of ADRBK1 Antibody (N-term) LS-C97473 in MDA-MB231 cell line lysates (35 ug/lane). ADRBK1 (arrow) was detected using the purified Pab.

Western blot

Western blot of ADRBK1 (arrow) using rabbit polyclonal ADRBK1 Antibody (N-term) LS-C97473. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ADRBK1 gene (Lane 2).
Western blot of ADRBK1 (arrow) using rabbit polyclonal ADRBK1 Antibody (N-term) LS-C97473. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ADRBK1 gene (Lane 2).

Western blot

Western blot of ADRBK1 Antibody (N-term) LS-C97473 in MDA-MB231 cell line lysates (35 ug/lane). ADRBK1 (arrow) was detected using the purified Pab.
Western blot of ADRBK1 Antibody (N-term) LS-C97473 in MDA-MB231 cell line lysates (35 ug/lane). ADRBK1 (arrow) was detected using the purified Pab.

Western blot

Western blot of ADRBK1 (arrow) using rabbit polyclonal ADRBK1 Antibody (N-term) LS-C97473. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ADRBK1 gene (Lane 2).
Western blot of ADRBK1 (arrow) using rabbit polyclonal ADRBK1 Antibody (N-term) LS-C97473. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ADRBK1 gene (Lane 2).

Western blot

Western blot of ADRBK1 Antibody (N-term) LS-C97473 in MDA-MB231 cell line lysates (35 ug/lane). ADRBK1 (arrow) was detected using the purified Pab.
Western blot of ADRBK1 Antibody (N-term) LS-C97473 in MDA-MB231 cell line lysates (35 ug/lane). ADRBK1 (arrow) was detected using the purified Pab.


Requested From: 
Date Requested: 6/18/2018

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