Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Beta-adrenergic receptor kinase (ADRBK1) phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. ADRBK1 is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. The ADRBK1 gene spans approximately 23 kb and is composed of 21 exons.
Western blot of ADRBK1 (arrow) using rabbit polyclonal ADRBK1 Antibody (N-term) LS-C97473. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ADRBK1 gene (Lane 2).
Western blot of ADRBK1 Antibody (N-term) LS-C97473 in MDA-MB231 cell line lysates (35 ug/lane). ADRBK1 (arrow) was detected using the purified Pab.