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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ADRB3 Antibody (C‑Terminus) LS‑C11810
ADRB3 antibody LS-C11810 is an unconjugated rabbit polyclonal antibody to mouse ADRB3. Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C11810-100
100 µl
$725

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Product Description

ADRB3 antibody LS-C11810 is an unconjugated rabbit polyclonal antibody to mouse ADRB3. Validated for ELISA and WB.
About ADRB3
The Beta-3 Adrenoceptor (ADRB3) is an Adrenergic Receptor that stimulates lipolysis and increases fatty acids in the blood. Stimulation of the beta-3 adrenoceptor leads to lipolysis in white adipocytes and nonshivering thermogenesis in brown fat. The beta-3 adrenoceptor has also been suggested to affect the physiological control of cardiac and vascular contractility; beta-3 adrenoceptor stimulation decreases cardiac contractility through activation of a nitric oxide synthase pathway. P13945 NM_000025 NP_000016.1

ADRB3 Antibody, Adrenoceptor beta 3 Antibody, ADRB3R Antibody, Adrenaline beta 3 receptor Antibody, Adrenergic, beta-3-, receptor Antibody, Beta-3 adrenergic receptor Antibody, B3AR Antibody, Beta-3 adrenoceptor Antibody, Beta3-AR Antibody, Beta-3 adrenoreceptor Antibody, BETA3AR Antibody


Specifications

Target
Mouse ADRB3
Host
Rabbit
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • Western blot (1:1000 - 1:5000)
  • ELISA (1:10000 - 1:100000)
Immunogen
ADRB3 antibody was raised against a 19 amino acid peptide sequence mapping at the C-terminus of the mouse B3AR (2) was used to generate anti- B3AR. The peptide was coupled with KLH (carrier protein).
Epitope
C-Terminus
Specificity
The 20 AA mouse B3AR immunogenic peptide sequence is 85% homologous with rat B3AR (17/20). It has no significant homology with the human B3AR. Anti-B3AR11 antibodies are not likely to cross-react with mouse/rat B3AR. Actual cross-reactivity of antibodies in all species is not established. Control peptides, because of their low MW (<3kD), are not suitable for Western. It should be used for ELISA or antibody blocking to confirm antibody specificity.
Usage
Suitable for use in ELISA, Western Blot. Western Blot: 1:1000-1:5000 for neat serum and 1-10 ug/ml for affinity pure using ECL. ELISA: 1:10000-1:100000 using 50-100 ng B3AR control peptide/well.
Presentation
PBS, 0.05% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/16/2018

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