Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
ADRB2 is beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor.
IHC of paraffin-embedded human brain, using Adrenergic Receptor B2 (Phospho-Ser355+Ser356) Antibody. The sample on the right was incubated with synthetic peptide.
Western blot of extracts from HUVEC cells treated with serum 20% 15' and COS7 cells treated with serum 20% 15', using Adrenergic Receptor B2 (Phospho-Ser355+Ser356) Antibody. The lane on the right was incubated with synthetic peptide.
Requested From: United States
Date Requested: 12/6/2016