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| Catalog Number | Size | Price |
|---|---|---|
| LS-A981-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human ADGRB2 / BAI2 Antibody (N‑Terminus, IHC) LS‑A981
PathPlus™ Polyclonal Rabbit anti‑Human ADGRB2 / BAI2 Antibody (N‑Terminus, IHC) LS‑A981
Antibody:
ADGRB2 / BAI2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
ADGRB2 / BAI2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
ADGRB2 (brain-specific angiogenesis inhibitor 2, BAI2) is an Orphan-B adhesion GPCR with an unknown ligand. Decreased BAI2 expression is correlated with the formation of new blood vessels in a murine ischemic model. Mutations in this gene are correlated with progressive spastic paraparesis and other neurological symptoms. Mutations affect binding to the endocytic protein endophilin A1, which is a potential interacting partner for BAI2.
References: Hum Mutat. 2017 Dec; 38(12): 1751–1760.
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Monkey, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 19 amino acid peptide from N-Terminus extracellular domain of human BAI2. Percent identity with other species by BLAST analysis: Human, Gorilla, Marmoset (100%); Orangutan, Monkey, Horse (95%); Hamster, Elephant, Panda, Pig (89%); Gibbon, Mouse, Rat, Dog (84%).
Epitope
N-Terminus
Specificity
Human BAI2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (14 - 21 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Failed Applications
- ICC
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ADGRB2 / BAI2
Validation
Anti-BAI2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BAI2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Lung, small cell carcinoma
Lung, small cell carcinoma
Brain, Amygdala, neurons and glia
Brain, Amygdala, neurons and glia
Anti-BAI2 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BAI2 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BAI2 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BAI2 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BAI2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-BAI2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ ADGRB2 / BAI2 Antibody (N-Terminus) for IHC LS-A981 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Guinea pig
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse, Rat, Dog, Hamster, Horse, Pig
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse, Rat, Dog, Hamster, Horse, Pig
Applications:
IHC, IHC - Paraffin
Source:
Human
Tag:
Myc-DDK (Flag)
Species:
Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/16/2024
Date Requested: 4/16/2024
