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Anti-ADAMTS5 Antibody (N-Terminus) IHC-plus™ LS-A1534

Catalog Size Price
LS-A1534-50 50 µg (1 mg/ml) Unavailable
Same day shipping In Stock - Same day shipping

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100% Guaranteed In Stock
Rabbit Polyclonal to Human ADAMTS5
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Details

Human ADAMTS5
Rabbit
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

IHC - Paraffin (14 µg/ml)

Specificity and Use

ADAMTS5 antibody was raised against synthetic 20 amino acid peptide from N-terminus of human ADAMTS5. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset (95%); Panda, Pig (85%); Rat, Bovine (80%).
LS-E28312 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A1534. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
N-Terminus
Human ADAMTS5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Immunohistochemistry: LS-A1534 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A1534 was determined to be 14 ug/ml.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

About ADAMTS5

Q9UNA0 NM_007038 NP_008969.2

ADAMTS5 Antibody, Aggrecanase-2 Antibody, ADAM-TS 11 Antibody, ADAM-TS5 Antibody, ADAMTS-11 Antibody, ADAMTS11 Antibody, ADAM-TS 5 Antibody, ADAMTS-5 Antibody, ADMP-2 Antibody, ADMP2 Antibody

ADAMTS5 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.

Immunohistochemistry

Immunohistochemistry
Anti-ADAMTS5 antibody LS-A1534 IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: 
Date Requested: 12/14/2017

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