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Anti-ADAM17 / TACE Antibody (clone 1F6) IHC-plus™ LS-B4426

Note: This antibody replaces LS-C105036

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $450
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ADAM17 / TACE Antibodies

Anti-ADAM17 / TACE Antibody (C-Terminus) LS-C263
Rabbit Polyclonal to Human ADAM17 / TACE
Human, Mouse, Rat
ICC, Western blot
Unconjugated
Immunocytochemistry Image
Anti-ADAM17 / TACE Antibody (aa807-823) IHC-plus™ LS-B619
Rabbit Polyclonal to Human ADAM17 / TACE
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-ADAM17 / TACE Antibody (clone 1F6) IHC-plus™ LS-B4426
Mouse Monoclonal [clone 1F6] (IgG2b,k) to Human ADAM17 / TACE
Human
IHC - Paraffin, Western blot, ELISA, Proximity Ligation Assay
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 1F6] (IgG2b,k) to Human ADAM17 / TACE
Human
IHC - Paraffin, Western blot, ELISA, Proximity Ligation Assay
Unconjugated

Details

Human ADAM17 / TACE
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b,k Monoclonal [1F6]
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot (1:500 - 1:1000)
  • ELISA
  • Proximity Ligation Assay

Specificity and Use

ADAM17 / TACE antibody was raised against aDAM17 (NP_003174, 215 a.a. ~ 315 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Western blot performed with the recombinant protein used as the immunogen. In situ Proximity Ligation Assay (Cell).

Packaging

PBS, pH 7.4. Sourced in Ascites.
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
For research use only.

About ADAM17 / TACE

P78536 NM_003183 NP_003174.3

ADAM17 Antibody, CD156B Antibody, CD156b antigen Antibody, CSVP Antibody, ADAM 17 Antibody, NISBD Antibody, TNF-alpha converting enzyme Antibody, TNF-alpha convertase Antibody, TNF-alpha-converting enzyme Antibody, Snake venom-like protease Antibody, TACE Antibody

Tumor-necrosis factor-a is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-a is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-a. TNF-a converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately.

Immunohistochemistry

Immunohistochemistry
Anti-ADAM17 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4426 concentration 5 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-ADAM17 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4426 concentration 5 ug/ml.

Enzyme-Linked Immunosorbent Assay

Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged ADAM17 is approximately 3 ng/ml as a capture antibody.

Proximity Ligation Assay

Proximity Ligation Assay
Proximity Ligation Analysis (PLA) of protein-protein interactions between TGFA and ADAM17. HeLa cells were stained with anti-TGFA rabbit purified polyclonal 1:1200 and anti-ADAM17 mouse monoclonal antibody 1:50. Signals were detected by Duolink 30 Detection.

Requested From: United States
Date Requested: 12/4/2016

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