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Anti-ADAM17 / TACE Antibody (C-Terminus) IHC-plus™ LS-B1821

Note: This antibody replaces LS-C46887


Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular ADAM17 / TACE Antibodies

Anti-ADAM17 / TACE Antibody (C-Terminus) LS-C263
Rabbit Polyclonal to Human ADAM17 / TACE
Human, Mouse, Rat
ICC, Western blot
Immunocytochemistry Image
Anti-ADAM17 / TACE Antibody (aa807-823) IHC-plus™ LS-B619
Rabbit Polyclonal to Human ADAM17 / TACE
Human, Mouse, Rat
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-ADAM17 / TACE Antibody (clone 1F6) IHC-plus™ LS-B4426
Mouse Monoclonal [clone 1F6] (IgG2b,k) to Human ADAM17 / TACE
IHC - Paraffin, Western blot, ELISA, Proximity Ligation Assay
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human ADAM17 / TACE
IHC - Paraffin, Western blot, ELISA


Human ADAM17 / TACE
Human (tested or 100% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (20 µg/ml)
  • Western blot (1 µg/ml)
  • ELISA (1 µg/ml)

Specificity and Use

ADAM17 / TACE antibody was raised against synthetic peptide from human ADAM17.
synthetic peptide corresponding to C-terminal residues of human ADAM 17 (a disintegrin and metalloproteinase domain 17 isoform 1 preproprotein)
Immunohistochemistry: LS-B1821 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1821 was determined to be 20 ug/ml.


PBS, 0.01% sodium azide, 50% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About ADAM17 / TACE

P78536 NM_003183 NP_003174.3

ADAM17 Antibody, CD156B Antibody, CD156b antigen Antibody, CSVP Antibody, ADAM 17 Antibody, NISBD Antibody, TNF-alpha converting enzyme Antibody, TNF-alpha convertase Antibody, TNF-alpha-converting enzyme Antibody, Snake venom-like protease Antibody, TACE Antibody

Tumor-necrosis factor-a is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-a is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-a. TNF-a converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately.


Anti-ADAM17 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1821 concentration 20 ug/ml.

Requested From: United States
Date Requested: 10/25/2016

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