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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ADAM10 Antibody LS‑C48244
Antibody
ADAM10 antibody LS-C48244 is an unconjugated rabbit polyclonal antibody to human ADAM10. Validated for WB.
Catalog
Size
Price
LS-C48244-100
100 µg (0.5 mg/ml)
Unavailable

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Applications: Western blot

Product Description

ADAM10 antibody LS-C48244 is an unconjugated rabbit polyclonal antibody to human ADAM10. Validated for WB.
About ADAM10
Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein. O14672 NM_001110 NP_001101.1

ADAM10 Antibody, AD10 Antibody, ADAM 10 Antibody, Kuzbanian Antibody, HsT18717 Antibody, CD156c Antibody, CD156c antigen Antibody, CDw156 Antibody, Kuz Antibody, Kuzbanian protein homolog Antibody, MADM Antibody


Specifications

Target
Human ADAM10
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 µg/ml)
Immunogen
ADAM10 antibody was raised against synthetic peptide corresponding to residue surrounding amino acid 735 of human ADAM10.
Specificity
The antibody detects 85 kD precursor form and 60 kD processed mature form of ADAM10.
Presentation
PBS, pH 7.2, 50% glycerol, 1% BSA, 0.02% sodium azide.
Storage
Short term: -20°C; Long term: -70°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/23/2018

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