Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
ACVR2A Antibody, ACTRIIA Antibody, Activin receptor type IIA Antibody, ACTRII Antibody, Activin A receptor type II Antibody, Activin receptor type-2A Antibody, ACTR-IIA Antibody, Activin A receptor, type II Antibody, Activin A receptor, type IIA Antibody, ACVR2 Antibody
ACVR2 / ACVR2A is a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner.
Anti-ACVR2A antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4803 concentration 5 ug/ml.
Western blot of ACVR2A (arrow) using rabbit polyclonal ACVR2A Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ACVR2A gene (Lane 2) (Origene Technologies).
Western blot of anti-ACVR2A Antibody in mouse liver(lane 1) brain(lane 2) and kidney(lane 3) tissue lysates (35 ug/lane). ACVR2A (arrow) was detected using the purified antibody.