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ACTN4

actinin, alpha 4

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.

Gene Name: actinin, alpha 4
Synonyms: ACTN4, ACTININ-4, Actinin, alpha 4, Actinin alpha4 isoform, FSGS1, F-actin cross-linking protein, Non-muscle alpha-actinin 4, Alpha-actinin-4, FSGS
Target Sequences: NM_004924 NP_004915.2 O43707

☰ Filters
Antibodies (45)
ELISA Kits (8)
Proteins (6)
Custom (4)
Over-Expression Lysate (2)
Primary (45)
Recombinant (4)
Sandwich (4)
ACTN4 (59)
Human (49)
Mouse (14)
Rat (11)
Bat (3)
Bovine (4)
Chicken (4)
Chimpanzee (6)
Dog (4)
Gibbon (6)
Guinea pig (3)
Hamster (1)
Horse (3)
Monkey (4)
Orangutan (6)
Pig (12)
Rabbit (3)
Xenopus (3)
Zebrafish (3)
IHC (15)
IHC-Fr (1)
IHC-P (7)
WB (41)
Flo (2)
ELISA (8)
ICC (4)
IF (6)
IP (5)
Peptide-ELISA (1)
rabbit (43)
mouse (2)
Product Group
IHCPlus (1)
IgG (27)
IgG2a,k (1)
monoclonal mc (2)
polyclonal pc (43)
4D10 (1)
93 (1)
96-Well Microplate (1)
96-Well Strip Plate (7)
APC (1)
APC Conjugated (2)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (2)
Unconjugated (24)
aa1-269 (8)
aa201-250 (4)
aa800-849 (4)
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aa1-50 (1)
aa192-220 (1)
aa206-542 (1)
aa27-38 (1)
aa28-38 (1)
aa397-648 (1)
aa785-813 (1)
No (59)
Cell Culture Supernatants (1)
Cell Lysates (1)
Plasma (3)
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His-T7 (1)
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Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
ACTN4 Antibody - Anti-ACTN4 / Alpha-Actinin-4 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ACTN4 Mouse anti-Human Monoclonal (4D10) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ACTN4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$783
ACTN4 Protein - 12.5% SDS-PAGE of human ACTN4 stained with Coomassie Blue
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Wheat Germ Extract
GST
131.3 kDa
10 µg/$479; 25 µg/$670
ACTN4 Antibody - Immunocytochemical analysis of Actinin-4 distribution in rat kidney using anti-alpha-Actinin-4, pAb (IG-701). Glomeruli are strongly labeled (frozen sections of formaldehyde perfused tissue (dilution 1:1600)).
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ACTN4 Rabbit anti-Human Polyclonal (aa27-38) Antibody
Mouse, Rat, Hamster, Pig, Human
ICC, IHC, IP, WB
Unconjugated
50 µg/$626
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ACTN4 Rabbit anti-Human Polyclonal (aa28-38) Antibody
Mouse, Dog, Bovine, Rat, Human, Monkey
IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µg/$890
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ACTN4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
100 µg/$331
ACTN4 Antibody - IHC of paraffin-embedded A549 xenograft using alpha Actinin 4 antibody at 1:500 dilution.
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ACTN4 Rabbit anti-Human Polyclonal (aa206-542) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
ACTN4 Antibody - Formalin-fixed and paraffin-embedded human breast carcinoma reacted with ACTN4 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ACTN4 Rabbit anti-Human Polyclonal (aa785-813) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
ACTN4 Antibody - Immunohistochemistry image of paraffin-embedded human lung tissue at a dilution of 1:100
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ACTN4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
ACTN4 Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer using ACTN4 Polyclonal Antibody at dilution of 1:60.
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ACTN4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ACTN4 Antibody - Alpha Actinin 4 was detected in paraffin-embedded sections of mouse kidney tissues using rabbit anti- Alpha Actinin 4 Antigen Affinity purified polyclonal antibody
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ACTN4 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ACTN4 Antibody - Western blot of ACTN4 antibody.
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ACTN4 Rabbit anti-Human Polyclonal (aa1-269) Antibody
Pig, Human
ICC, IP, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
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ACTN4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
Select
ACTN4 Rabbit anti-Human Polyclonal (aa397-648) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
ACTN4 Antibody - Western blot of mouse whole brain lysate showing specific immunolabeling of the ~105 kDa a-actinin 4 protein.
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ACTN4 Mouse anti-Human Monoclonal (93) Antibody
Mouse, Human
IHC, WB
Unconjugated
100 µl/$469
ACTN4 Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ACTN4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ACTN4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
ACTN4 Antibody - Western blot of anti-ACTN4 Antibody in HeLa cell line lysates (35 ug/lane). ACTN4 (arrow) was detected using the purified antibody.
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ACTN4 Rabbit anti-Human Polyclonal (aa192-220) Antibody
Human
IHC, WB
Unconjugated
400 µl/$393
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ACTN4 Rabbit anti-Human Polyclonal Antibody
Human
ICC, WB
Unconjugated
100 µg/$749
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ACTN4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
IF, WB
Biotin Conjugated
100 µl/$937
Select
ACTN4 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
IF, WB
FITC Conjugated
100 µl/$937
Select
ACTN4 Rabbit anti-Human Polyclonal (APC) Antibody
Human
IF, WB
APC Conjugated
100 µl/$937
Select
ACTN4 Rabbit anti-Human Polyclonal (PE) Antibody
Human
IF, WB
PE Conjugated
100 µl/$937
ACTN4 Antibody - IHC testing of FFPE human intestinal cancer tissue with ACTN4 antibody at 1ug/ml. HIER: steam in pH6 citrate buffer and allow to cool prior to staining.
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ACTN4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µg/$575
ACTN4 Antibody - Western blot analysis of extracts from 293 cells, HeLa cells and A549 cells, using ACTN4 antibody.
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ACTN4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
Viewing 1-25 of 59 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).