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| Catalog Number | Size | Price |
|---|---|---|
| LS-B4203-50 | 50 µl (0.81 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human ACTA1 / Skeletal Muscle Actin Antibody (IHC, WB) LS‑B4203
PathPlus™ Polyclonal Rabbit anti‑Human ACTA1 / Skeletal Muscle Actin Antibody (IHC, WB) LS‑B4203
Note: This antibody replaces LS-C109342
Antibody:
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Fish, Zebrafish
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
ACTA1 / Skeletal Muscle Actin Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Fish, Zebrafish
Format:
Unconjugated, Unmodified
Specifications
Description
Muscle actin (ACTA1, ACTA) is a protein that is a major component of the contractile apparatus of the cytoskeleton in muscle tissues. Mutations of the ACTA1 gene result in nemaline myopathy type 3. It is expressed in skeletal muscle, smooth muscle, heart muscle, myoepithelial cells, myofibroblasts, pericytes, and decidual cells. Staining is used to identify skeletal muscle and smooth muscle cells in normal tissues and in disease to distinguish soft-tissue tumors with muscle differentiation (eg, rhabdomyoma, rhabdomyosarcoma, leiomyoma, leiomyosarcoma) from other types of tumors.
References:
Am J Clin Pathol. 1991;96(1):32-45. PMID: 1712542; Cardiovasc Pathol. 2006;15(2):91-99. doi: 10.1016/j.carpath.2005.11.006; Am J Otolaryngol. 2005;26(3):201-206. PMID: 15858778; Nat Genet. 1999;23(2):208-212. doi: 10.1038/13837
Target
Human ACTA1 / Skeletal Muscle Actin
Synonyms
ACTA1 | ACTA | Actin, alpha skeletal muscle | Alpha-actin-1 | CFTD | CFTD1 | CFTDM | MPFD | NEM1 | NEM2 | ASMA | NEM3
Host
Rabbit
Reactivity
Human, Fish, Zebrafish
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Recombinant protein encompassing a sequence within the center region of human alpha Skeletal Muscle Actin. The exact sequence is proprietary.
Specificity
Human and zebrafish alpha Actin (skeletal muscle). Predicted cross-reactivity based on amino acid sequence homology: bovine (100%).
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- Western blot (1:500 - 1:3000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
1X PBS, pH 7, 0.025% ProClin™ 300, 20% Glycerol
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ACTA1 / Skeletal Muscle Actin
Validation
Human Breast, Myoepithelial Cells: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Breast, Myoepithelial Cells: Formalin-Fixed, Paraffin-Embedded (FFPE)
Anti-ACTA1 / ASMA antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-ACTA1 / ASMA antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-ACTA1 / ASMA antibody IHC of human lung, bronchial smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-ACTA1 / ASMA antibody IHC of human lung, bronchial smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
See More About...
LSBio Ratings
PathPlus™ ACTA1 / Skeletal Muscle Actin Antibody for IHC, WB/Western LS-B4203 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (1)
How Different Stocking Densities Affect Growth and Stress Status of Acipenser baerii Early Stage Larvae. Lucia Aidos, Alessandra Cafiso, Valentina Serra, Mauro Vasconi, Daniela Bertotto, Chiara Bazzocchi, Giuseppe Radaelli, Alessia Di Giancamillo. Animals: an open access journal from MDPI. 2020 July;10:
Customer Reviews (0)
Featured Products
Species:
Human, Rat, Goat, Pig, Rabbit
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Species:
Human
Applications:
IHC, Western blot, Flow Cytometry, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC, ICC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Species:
Human
Applications:
IHC, ICC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Reactivity:
Human, Mouse, Rat
Range:
Positive/Negative
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
