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ACOT8

acyl-CoA thioesterase 8

Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxisome proliferation.

Gene Name: acyl-CoA thioesterase 8
Synonyms: ACOT8, Acyl-CoA thioesterase 8, Acyl-coenzyme A thioesterase 8, ACTEIII, HNAACTE, HACTE-III, HACTEIII, PTE-1, Thioesterase II, Palmitoyl-CoA hydrolase, PTE1, Choloyl-CoA hydrolase, HTE, PTE-2, PTE2, Thioesterase III
Target Sequences: NM_005469 NP_005460.2 O14734

☰ Filters
Antibodies (27)
Proteins (8)
Over-Expression Lysate (4)
Primary (27)
Recombinant (4)
ACOT8 (35)
Human (27)
Mouse (10)
Rat (3)
Chimpanzee (3)
Gibbon (3)
Monkey (4)
Orangutan (3)
IHC (10)
IHC-P (3)
WB (27)
Flo (8)
ELISA (15)
ICC (2)
IF (7)
Peptide-ELISA (2)
rabbit (19)
mouse (8)
Product Group
IHCPlus (1)
IgG (13)
IgG1,k (6)
IgG2a,k (1)
monoclonal mc (7)
polyclonal pc (20)
AT4D10 (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (14)
aa290-319 (7)
N-Terminus (4)
100-180 aa, Internal (1)
Internal (1)
aa108-215 (1)
aa131-180 (1)
No (35)
GST (1)
GST, N-terminus (1)
His (1)
His, N-Terminal (1)
Myc-DDK (Flag) (4)
Human (6)
293T Cells (2)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
ACOT8 Antibody - Immunohistochemical analysis of ACOT8 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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ACOT8 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
ACOT8 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ACOT8 Rabbit anti-Human Polyclonal (aa131-180) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
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ACOT8 Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
ACOT8 Antibody - ACOT8 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACOT8 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
ACOT8 Antibody - ACOT8 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACOT8 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human, Monkey, Chimpanzee, Orangutan, Gibbon
WB
Biotin Conjugated
100 µl/$469
ACOT8 Antibody - Western blot analysis of extracts of various cell lines, using ACOT8 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
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ACOT8 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
ACOT8 Antibody - Formalin-fixed and paraffin-embedded human Prostate carcinoma reacted with ACOT8 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ACOT8 Rabbit anti-Human Polyclonal (aa290-319) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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ACOT8 Rabbit anti-Human Polyclonal (aa290-319) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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ACOT8 Rabbit anti-Human Polyclonal (aa290-319) (Biotin) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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ACOT8 Rabbit anti-Human Polyclonal (aa290-319) (FITC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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ACOT8 Rabbit anti-Human Polyclonal (aa290-319) (PE) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
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ACOT8 Rabbit anti-Human Polyclonal (aa290-319) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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ACOT8 Rabbit anti-Human Polyclonal (aa290-319) (APC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
ACOT8 Antibody - ICC/IF analysis of ACOT8 in A549 cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human ACOT8 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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ACOT8 Mouse anti-Human Monoclonal (AT4D10) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
ACOT8 Antibody - Western blot of ACOT8 antibody
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ACOT8 Rabbit anti-Human Polyclonal (100-180 aa, Internal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ACOT8 Antibody - Peptide - + Immunofluorescence analysis of A549 cells, using ACOT8 antibody.
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ACOT8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
ACOT8 Antibody - Staining HuvEc cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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ACOT8 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ACOT8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
100 µl/$386
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ACOT8 Mouse anti-Human Monoclonal (aa108-215) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
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ACOT8 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
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ACOT8 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
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ACOT8 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
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ACOT8 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
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ACOT8 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
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ACOT8 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Viewing 1-25 of 35 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).