Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Paraffin, ICC, Western blot, Flow Cytometry, ELISA
Human ACKR2 / CCR10 / D6
Human (tested or 100% immunogen sequence identity)
IHC - Paraffin
Western blot (1:1000)
Specificity and Use
ACKR2 / CCR10 / D6 antibody was raised against synthetic peptide: C-LATEDADSENSSFYYYDYLDEVAFML (Human). Percent identity by BLAST analysis: Human (100%); Gorilla (96%); Gibbon (88%); Marmoset (81%).
Recognizes human Chemokine Receptor D6. Peptide sequence is < 50% identical to other human chemokine receptors in this region.
Suitable for use in Western Blot, ELISA, Immunohistochemistry (Formalin-fixed paraffin-embedded sections), Immunocytochemistry and Flow Cytometry/FACS. ELISA: 1:100000. FACS: 1-3 ul/1E6cells/50-100ul. Immunocytochemistry: 1:400. Immunohistochemistry (Paraffin): 1:250. Western Blot: 1:1000.
Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor.