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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ACKR2 / CCR10 / D6 Antibody (aa335‑384) IHC‑plus™ LS‑B8985
Note: This antibody replaces LS-C120564
D6 antibody LS-B8985 is an unconjugated rabbit polyclonal antibody to human D6 (ACKR2 / CCR10). Validated for IF, IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B8985-50
50 µl
Unavailable

Popular ACKR2 / CCR10 / D6 Products

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Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot

Product Description

D6 antibody LS-B8985 is an unconjugated rabbit polyclonal antibody to human D6 (ACKR2 / CCR10). Validated for IF, IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues.
About ACKR2 / CCR10 / D6
Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. O00590 NM_001296 NP_001287.2

ACKR2 Antibody, C-C chemokine receptor D6 Antibody, CCBP2 Antibody, Chemokine (C-C) receptor 9 Antibody, Chemokine binding protein 2 Antibody, C-C chemokine receptor 10 Antibody, Chemokine-binding protein 2 Antibody, CMKBR9 Antibody, Chemokine receptor CCR-9 Antibody, G protein coupled receptor d6 Antibody, HD6 Antibody, Cc-chemokine receptor type 10 Antibody, Chemokine receptor CCR-10 Antibody, Chemokine receptor D6 Antibody, Chemokine-binding protein D6 Antibody, D6 Antibody


Specifications

Target
Human ACKR2 / CCR10 / D6
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:200)
  • Immunofluorescence (1:100 - 1:500)
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide from human CCBP2 (aa335-384).
Epitope
aa335-384
Specificity
CCBP2 Antibody detects endogenous levels of total CCBP2 protein.
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-ACKR2 / CCR10 / D6 antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ACKR2 / CCR10 / D6 antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunofluorescence

Immunofluorescence of COS7 cells, using CCBP2 Antibody. The picture on the right is treated with the synthesized peptide.
Immunofluorescence of COS7 cells, using CCBP2 Antibody. The picture on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from HepG2 cells, using CCBP2 Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HepG2 cells, using CCBP2 Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry

Anti-ACKR2 / CCR10 / D6 antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ACKR2 / CCR10 / D6 antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunofluorescence

Immunofluorescence of COS7 cells, using CCBP2 Antibody. The picture on the right is treated with the synthesized peptide.
Immunofluorescence of COS7 cells, using CCBP2 Antibody. The picture on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from HepG2 cells, using CCBP2 Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HepG2 cells, using CCBP2 Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry

Anti-ACKR2 / CCR10 / D6 antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ACKR2 / CCR10 / D6 antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunofluorescence

Immunofluorescence of COS7 cells, using CCBP2 Antibody. The picture on the right is treated with the synthesized peptide.
Immunofluorescence of COS7 cells, using CCBP2 Antibody. The picture on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from HepG2 cells, using CCBP2 Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HepG2 cells, using CCBP2 Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry

Anti-ACKR2 / CCR10 / D6 antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ACKR2 / CCR10 / D6 antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunofluorescence

Immunofluorescence of COS7 cells, using CCBP2 Antibody. The picture on the right is treated with the synthesized peptide.
Immunofluorescence of COS7 cells, using CCBP2 Antibody. The picture on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from HepG2 cells, using CCBP2 Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HepG2 cells, using CCBP2 Antibody. The lane on the right is treated with the synthesized peptide.


Requested From: 
Date Requested: 6/24/2018

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