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Acetyl-CoA Carboxylase / ACC

acetyl-CoA carboxylase alpha

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.

Gene Name: acetyl-CoA carboxylase alpha
Synonyms: ACACA, ACAC, ACC1, ACACAD, ACCA, ACC, ACC-alpha, Acetyl-CoA Carboxylase, Acetyl-CoA carboxylase 1, Acetyl-CoA carboxylase alpha
Target Sequences: Q13085 Q13085

Publications (2)

1
Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin. Wong GW, Krawczyk SA, Kitidis-Mitrokostas C, Ge G, Spooner E, Hug C, Gimeno R, Lodish HF. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2009 23:241-58. (WB) [PubMed:18787108] [PMC:PMC2626616]
2
Effects of atypical antipsychotics and haloperidol on PC12 cells: only aripiprazole phosphorylates AMP-activated protein kinase. Takami G, Ota M, Nakashima A, Kaneko YS, Mori K, Nagatsu T, Ota A. Journal of neural transmission (Vienna, Austria : 1996). 2010 117:1139-53. (WB; Rat) [PubMed:20686905] Related Antibodies: LS-C11718.

☰ Filters
Antibodies (57)
ELISA Kits (16)
Proteins (9)
Cell-Based (1)
Competitive EIA (3)
Custom (3)
Over-Expression Lysate (2)
Primary (57)
Recombinant (7)
Sandwich (9)
Acetyl-CoA Carboxylase / ACC (82)
Human (56)
Mouse (46)
Rat (42)
Bovine (7)
Chicken (2)
Hamster (1)
Monkey (1)
Pig (3)
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rabbit (48)
mouse (9)
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monoclonal mc (10)
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pSer80 (10)
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aa2010-2039 (7)
aa73-85, pSer79 (6)
20-100 aa (4)
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aa46-95 (2)
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aa1925-1975 (1)
aa2333-C-term (1)
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Purified (6)
Acetyl-CoA Carboxylase / ACC Antibody - Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using ACC1 Antibody. The picture on the right is blocked with the synthesized peptide.
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Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Polyclonal (aa46-95) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Acetyl-CoA Carboxylase / ACC Antibody - Immunohistochemical analysis of ACC alpha (pS80) staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX. w
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Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Polyclonal (pSer80) Antibody
Mouse, Sheep, Bovine, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$315
Acetyl-CoA Carboxylase / ACC ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
Select
Acetyl-CoA Carboxylase / ACC Mouse anti-Rat Monoclonal (pSer79) (Azide-free) Antibody
Mouse, Rat
WB
Unconjugated, Azide-free
200 µg/$962
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Acetyl-CoA Carboxylase / ACC Rabbit anti-Rat Polyclonal (pSer79) Antibody
Rat, Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$717
Acetyl-CoA Carboxylase / ACC Antibody - Immunohistochemical analysis of ACC alpha (pS80) staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Polyclonal (pSer80) Antibody
Chicken, Sheep, Bovine, Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
Acetyl-CoA Carboxylase / ACC ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$818
Select
Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IP, WB
Unconjugated
100 µl/$688
Select
Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Sheep, Bovine, Rat, Pig, Human
ELISA, WB
Unconjugated
100 µg/$832
Select
Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Monoclonal (pSer523) Antibody
Mouse, Rat, Hamster, Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$688
Acetyl-CoA Carboxylase / ACC Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Acetyl-CoA Carboxylase Antibody. The picture on the right is blocked with the synthesized peptide.
Select
Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Polyclonal (aa46-95) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Polyclonal (pSer1263) Antibody
Human
IHC, WB
Unconjugated
100 µg/$480
Select
Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Polyclonal (aa2010-2039) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
Acetyl-CoA Carboxylase / ACC Mouse anti-Human Monoclonal (12K2) Antibody
Mouse, Human
WB
Unconjugated
100 µg/$896
Acetyl-CoA Carboxylase / ACC Antibody - ACACA Antibody western blot of 293 cell line lysates (35 ug/lane). The ACACA antibody detected the ACACA protein (arrow).
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Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Polyclonal (aa2010-2039) Antibody
Human
WB
Unconjugated
400 µl/$393
Select
Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Polyclonal (Lys557) Antibody
Mouse, Bovine, Rat, Human, Monkey
Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$688
Acetyl-CoA Carboxylase / ACC Antibody - 1:200 staining human liver carcinoma tissues by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Polyclonal (pSer80) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Acetyl-CoA Carboxylase / ACC Antibody - 1:100 staining mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
Acetyl-CoA Carboxylase / ACC Rabbit anti-Rat Polyclonal (pSer79) Antibody
Rat, Human
WB
Unconjugated
200 µg/$758
Acetyl-CoA Carboxylase / ACC Antibody - Anti-Acetyl-CoA Carboxylase / ACC antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Polyclonal (aa2333-C-term) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Acetyl-CoA Carboxylase / ACC Antibody - Anti-Acetyl-CoA Carboxylase / ACC antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Polyclonal (aa1925-1975) Antibody
Human
IHC, IHC-P, IP
Unconjugated
50 µl/$460
Acetyl-CoA Carboxylase / ACC Antibody - Acetyl-CoA Carboxylase Antibody in Western Blot (WB)
Select
Acetyl-CoA Carboxylase / ACC Mouse anti-Human Monoclonal (C-Terminus) (143) Antibody
Human
ELISA, IF, IP, WB
Unconjugated
100 µg/$504
Acetyl-CoA Carboxylase / ACC Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Acetyl-CoA Carboxylase / ACC Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Sheep, Bovine, Rat, Pig, Human
IHC-P, WB
Unconjugated
50 µl/$460
Acetyl-CoA Carboxylase / ACC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
259.5 kDa
20 µg/$215
Acetyl-CoA Carboxylase / ACC Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
10His, N-terminus
69.9 kDa
20 µg/$405; 1 mg/$1,679; 100 µg/$598
Viewing 1-25 of 82 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).