Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Frozen, ICC, Western blot, Immunoprecipitation, ELISA
Human ACE / CD143
Human, Monkey, Rat, Cat, Hamster (tested or 100% immunogen sequence identity)
IHC - Frozen
Western blot (1:100)
IHC - Paraffin
Specificity and Use
ACE / CD143 antibody was raised against angiotensin-converting enzyme from human lung
Angiotensin-converting enzyme [ACE] (N-terminal), no reactivity to testicular/germinal form of human ACE (90kD isoform)
Immunohistochemistry (Danilov et al., 1987; Falkenhahn et al., 1995; Morrell et al., 1995): 1:1000 on fresh frozen or 4% paraformaldehyde fixed tissues. Does not work on paraffin embedded tissue. Immunocytochemistry: 1:100. Reacts with endothelial cell, m
PBS, pH 7.4, 150 mM sodium chloride, 0.05% sodium azide
Store at -20°C. Aliquot to avoid freeze/thaw cycles. Store undiluted.
ACE Antibody, ACE1 Antibody, Angiotensin-converting enzyme Antibody, CD143 Antibody, CD143 antigen Antibody, Carboxycathepsin Antibody, DIPEPTIDYL CARBOXYPEPTIDASE Antibody, DCP Antibody, Dipeptidyl carboxypeptidase I Antibody, ICH Antibody, Kininase II Antibody, MVCD3 Antibody, Peptidyl-dipeptidase A Antibody, Peptidase P Antibody, DCP1 Antibody, Dipeptidyl carboxypeptidase 1 Antibody, Testicular ECA Antibody
ACE / CD143 is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system.