Human ACE / CD143

Mouse

Human (tested or 100% immunogen sequence identity)

Monoclonal

CG2

Unconjugated

Affinity purified

Unmodified

Purified ACE from human lung and kidney

The antigen is CD143, the epitope is apparently localized in the N-terminal portion of the protein. Antigen distribution: Tissue sections: Topographically the degree of expression correlates with the proportion of smooth muscle cells and elastic fibres of the vessel wall. ACE is predominantely expressed by small muscular arteries and by arterioles, whereas small and large veins do not usually express ACE. However, no ACE could be detected in the endothelial cells of kidney. Constitutively ACE is expressed on endothelial cells in different diseases like hypertension, myocardial infarction, sarcoidosis, diabetes. Specificity: Human: denatured ACE. Other species: not tested.

• IHC
• IHC - Paraffin (1:50)

Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.1% Kathon

Reconstitute with 0.5ml distilled H2O.

Store at 4°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P12821 NCBI: NM_000789 NP_000780.1