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ACD / PTOP

adrenocortical dysplasia homolog (mouse)

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by increasing telomerase processivity. Plays a role in shelterin complex assembly. May play a role in organogenesis.

Gene Name: adrenocortical dysplasia homolog (mouse)
Synonyms: ACD, PTOP, TIN2 interacting protein 1, TINT1, PIP1
Target Sequences: NM_022914 NP_075065.2 Q96AP0

Publications (1)

1
Transcriptome analyses of ovarian stroma: tunica albuginea, interstitium and theca interna. Katja Hummitzsch, Nicholas Hatzirodos, Anne M Macpherson, Jeff Schwartz, Raymond J Rodgers, Helen F Irving-Rodgers. Reproduction (Cambridge, England). 2019 Jun;;157:545-565. [Full Text Article] [PubMed:30925461] Related Antibodies: LS-C108067.

☰ Filters
Antibodies (51)
Proteins (12)
ELISA Kits (6)
Over-Expression Lysate (6)
Primary (51)
Recombinant (6)
Sandwich (6)
ACD / PTOP (69)
Human (43)
Mouse (17)
Rat (13)
Bovine (6)
Chicken (1)
Chimpanzee (3)
Dog (6)
Guinea pig (7)
Horse (6)
Monkey (4)
Porcine (1)
Rabbit (1)
IHC (3)
IHC-P (2)
WB (48)
Flo (2)
ELISA (5)
IF (5)
IP (1)
rabbit (43)
mouse (8)
IgG (24)
IgG1 (4)
IgG1,k (1)
IgG2b (2)
monoclonal mc (7)
polyclonal pc (44)
1D8-1B6 (1)
OTI1A2 (2)
OTI1C8 (2)
OTI2B1 (2)
96-Well Strip Plate (6)
APC (2)
APC Conjugated (3)
Biotin Conjugated (7)
Carrier-free (3)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (3)
Unconjugated (20)
aa147-342 (8)
aa21-175 (8)
C-Terminus (4)
aa398-447 (4)
aa467-516 (4)
aa66-348 (1)
No (68)
Yes (1)
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Serum (1)
GST (1)
His, N-Terminal (1)
His-T7 (2)
Myc-DDK (Flag) (8)
Human (7)
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293T Cells (3)
E. coli (3)
HEK 293 Cells (5)
Wheat Germ Extract (1)
Purified (2)
ACD / PTOP Antibody - ACD / PTOP antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACD / PTOP Rabbit anti-Human Polyclonal (aa467-516) Antibody
Human
WB
Unconjugated
100 µl/$424
ACD / PTOP Antibody - Immunoperoxidase of monoclonal antibody to ACD on formalin-fixed paraffin-embedded human heart tissue. [antibody concentration 2 ug/ml].
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ACD / PTOP Mouse anti-Human Monoclonal (1D8-1B6) Antibody
Human
ELISA, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$423
ACD / PTOP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-ACD mouse monoclonal antibody.
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ACD / PTOP Mouse anti-Human Monoclonal (OTI2B1) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
ACD / PTOP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-ACD mouse monoclonal antibody.
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ACD / PTOP Mouse anti-Human Monoclonal (Carrier-free) (OTI2B1) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ACD / PTOP Antibody - Anti-ACD mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACD.
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ACD / PTOP Mouse anti-Human Monoclonal (OTI1A2) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
ACD / PTOP Antibody - Anti-ACD mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACD.
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ACD / PTOP Mouse anti-Human Monoclonal (Carrier-free) (OTI1A2) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
ACD / PTOP Antibody - Anti-ACD mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACD.
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ACD / PTOP Mouse anti-Human Monoclonal (OTI1C8) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
ACD / PTOP Antibody - Anti-ACD mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACD.
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ACD / PTOP Mouse anti-Human Monoclonal (Carrier-free) (OTI1C8) Antibody
Human
IF, WB
Unconjugated, Carrier-free
100 µg/$511
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ACD / PTOP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$332
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ACD / PTOP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
ACD / PTOP Antibody - Positive Western Blot detected in Mouse spleen tissue. All lanes: ACD antibody at 4 µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 58 KDa. Observed band size: 58 KDa
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ACD / PTOP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
ACD / PTOP Antibody - Western blot analysis of HEPG2 cell lysate  using ACD Polyclonal Antibody at dilution of 1:400
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ACD / PTOP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ACD / PTOP Antibody - ACD / PTOP antibody Western blot of Mouse Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACD / PTOP Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
WB
Unconjugated
100 µl/$424
ACD / PTOP Antibody - ACD / PTOP antibody Western blot of Mouse Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACD / PTOP Rabbit anti-Mouse Polyclonal (C-Terminus) (HRP) Antibody
Mouse, Dog, Guinea pig, Bovine, Horse, Human
WB
HRP Conjugated
100 µl/$469
ACD / PTOP Antibody - ACD / PTOP antibody Western blot of Mouse Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACD / PTOP Rabbit anti-Mouse Polyclonal (C-Terminus) (Biotin) Antibody
Mouse, Dog, Guinea pig, Bovine, Horse, Human
WB
Biotin Conjugated
100 µl/$469
ACD / PTOP Antibody - ACD / PTOP antibody Western blot of Mouse Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACD / PTOP Rabbit anti-Mouse Polyclonal (C-Terminus) (FITC) Antibody
Mouse, Dog, Guinea pig, Bovine, Horse, Human
WB
FITC Conjugated
100 µl/$469
ACD / PTOP Antibody - Western blot of ACD / PTOP antibody.
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ACD / PTOP Rabbit anti-Mouse Polyclonal (aa21-175) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
ACD / PTOP Antibody - Western blot of ACD / PTOP antibody.
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ACD / PTOP Rabbit anti-Mouse Polyclonal (aa21-175) (HRP) Antibody
Mouse, Human
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
ACD / PTOP Antibody - Western blot of ACD / PTOP antibody.
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ACD / PTOP Rabbit anti-Mouse Polyclonal (aa21-175) (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
ACD / PTOP Antibody - Western blot of ACD / PTOP antibody.
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ACD / PTOP Rabbit anti-Mouse Polyclonal (aa21-175) (APC, Cy7) Antibody
Mouse, Human
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
ACD / PTOP Antibody - Western blot of ACD / PTOP antibody.
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ACD / PTOP Rabbit anti-Mouse Polyclonal (aa21-175) (Cy3) Antibody
Mouse, Human
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
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ACD / PTOP Rabbit anti-Human Polyclonal (aa66-348) Antibody
Human
WB
Unconjugated
50 µg/$414
Select
ACD / PTOP Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
ACD / PTOP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
ACD / PTOP Antibody - Fetal brain lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACD / PTOP Rabbit anti-Human Polyclonal (aa398-447) Antibody
Human
WB
Unconjugated
100 µl/$424
Viewing 1-25 of 69 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).